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CompletedNCT07276113Updated Dec 10, 2025

Enriched Eggs as a Sustainable Approach to Enhance Omega-3 Status in Elite Athletes

An interventional study of omega-3 enriched eggs and non-enriched eggs in Suboptimal Omega-3 Index, sponsored by Queen's University, Belfast. Completed at 2 sites in 2 countries. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-10.

Sponsored by Queen's University, Belfast · Not applicable, Interventional, and Other

From the registry’s dates

  • Registered 2 years 1 month after the study started (first participant enrolled Sep 2023, registered Nov 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
17
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The study looked to identify the benefit of omega-3 enriched eggs on circulating omega-3 fatty acid profile of elite level athletes

Read the detailed description

Study hypothesis: Consuming omega-3 enriched eggs (compared to control) will (1) increase omega-3 index whilst also (2) improving subjective markers of recovery and other health parameters.

Aims \& objective:

Overall aim: To investigate the impact of consuming omega-3 enriched eggs blood fatty acid profile among elite level athletes who do not reach omega-3 index targets of 8%, compared to control. Secondary data collected will analyse the impact on health and recovery parameters.

Primary objective: To assess the effect of consuming omega-3 enriched eggs on blood fatty acid response (omega-3 index) in elite level athletes.

Secondary objective: To assess the effect of consuming omega-3 enriched eggs on subjective recovery markers using validated questionnaires (RESTQ-Sport-36, appendix 1; Acute Recovery \& Stress Scale, appendix 2) and other health parameters including resting heart rate and blood pressure.

Recruitment Participants will be recruited from Sport Ireland Institute of Sport (SII). SII are partners for this PhD and will provide access for recruitment to those teams/ athletes based in Dublin. Further recruitment will be open to teams across the island of Ireland where potential participants are competing at the highest level within that sport. All relevant permissions will be obtained before commencing any recruitment strategy. All recruitment will initially require approval from the Head of Performance for that sport, this will allow for the researcher to provide athletes with an information sheet, screening questionnaire and consent form. Secondary recruitment will be via a poster which will be put up around the campus. This recruitment will be provided approval by relevant individuals in SII and QUB. The poster will have a QR code which links the interested party to the participant information sheet and screening questionnaire.

Primary objective data collection:

Participants from both omega-3 enriched group and control group will provide a dried blood spot at week 0 (before starting intervention) and post 8-week intervention. The first step is to increase blood flow to the hands; this is done by asking the participant to wash their hands in warm water. The tip of the index finger is prepared with an antibacterial wipe, and this is allowed to dry unassisted. A lancet is then used to draw blood with the first show of blood being wiped away with gauze. The finger is gently squeezed, allowing a blood drop to form. The blood drop is allowed to drop onto the designated spot of the collection card. The collection cards are pre-treated with a proprietary antioxidant treatment called OxyStop, this prevents oxidative loss of PUFAs. The sample is allowed to dry for a few minutes before being sent the same day to a commercial laboratory for analysis (OmegaQuant, University of Stirling, GB).

Co-investigators are familiar with collecting OmegaQuant blood samples through previous professional experience.

02

Conditions studied

  • Suboptimal Omega-3 Index
03

In context

Lead sponsor

Queen's University, Belfast is the lead sponsor of 113 studies on the registry; 14 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Participants must be elite level female athletes (tier 4 or 5)

Exclusion criteria

Exclusion Criteria:

  • Non-smokers
  • Must not be taking statins to lower LDL cholesterol levels.
  • Must not have high blood pressure (systolic >140/ diastolic >90mmHg)
  • Participants must remain injury free (not miss training >1week)
  • Baseline omega-3 index of \<8%
  • Currently include eggs as part of their habitual diet.
  • Participants must be willing to consume 14 eggs per week for 8 weeks.
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
17 participants (actual)

Study arms

  • Experimental
    Intervention

    omega-3 enriched egg (14 eggs weekly for 8 weeks, \~250mg DHA daily).

    Other: omega-3 enriched eggs

  • Placebo comparator
    Control

    Non enriched egg group (14 eggs per week for 8 weeks)

    Other: non-enriched eggs

Interventions

  • Otheromega-3 enriched eggs

    omega-3 enriched eggs

  • Othernon-enriched eggs

    non-omega-3 enriched eggs

06

What researchers measure

Primary outcomes

  1. omega-3 index

    Time frame: 8 weeks

07

Study locations

2 sites
  • Sport Ireland Institute
    Dublin, Dublin D15 Y52H, Ireland
  • Garvaghey Centre
    Omagh, Tyrone BT70 2EH, United Kingdom
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07276113
Lead sponsor
Queen's University, Belfast
Responsible party
Matthew Hooks (Mr, Queen's University, Belfast) — Principal investigator
First posted
Dec 10, 2025
Start date
Sep 25, 2023
Primary completion
Dec 9, 2024
Completion
Dec 31, 2024
Last update
Dec 10, 2025

Study contacts

Anne Nugent, Doctorate
principal investigator · Queens University Belfast

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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