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Not yet recruitingNCT07275008Updated Dec 10, 2025

Efficacy and Prognosis of Auxiliary Liver Transplantation

An observational study in Liver Transplantation and Auxiliary Liver Transplantation, sponsored by Zhi-Jun Zhu. Not yet recruiting. Per ClinicalTrials.gov, last updated 2025-12-10.

Sponsored by Zhi-Jun Zhu · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Sex
All
01

Study summary

The objective of this observational study is to systematically compare the efficacy and patient prognosis between auxiliary liver transplantation and living donor liver transplantation, and to explore the postoperative recovery, survival rate, rejection, postoperative complications, and long-term prognosis of patients undergoing auxiliary liver transplantation.

02

Conditions studied

  • Liver Transplantation
  • Auxiliary Liver Transplantation
03

In context

Lead sponsor

Zhi-Jun Zhu is the lead sponsor of 4 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients who were treated at the Liver Transplantation Center of Beijing Friendship Hospital, Capital Medical University between December 2025 and December 2028, and who underwent either auxiliary liver transplantation (study group) or conventional liver transplantation (control group).

Inclusion criteria

  1. Patients who underwent auxiliary liver transplantation or living donor liver transplantation (LDLT).
  2. Patients with complete medical records and follow-up data.

Exclusion criteria

Exclusion Criteria:

  1. Patients who underwent retransplantation.
  2. Patients who underwent other organ transplantation (or multiorgan transplantation).
  3. Patients with severe missing postoperative follow-up data or loss to follow-up.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • auxiliary liver transplantation

    Patients who underwent auxiliary liver transplantation at our center during the study period

  • living donor liver transplantation

    Patients who underwent traditional orthotopic living donor liver transplantation at our center during the study period.

06

What researchers measure

Primary outcomes

  1. Overall survival

    Time frame: Within one year after liver transplantation

Secondary outcomes

  1. Complications

    Rejection, vascular, biliary and other related complications

    Time frame: Within one year after liver transplantation

  2. changes in peripheral blood lymphocytes

    Peripheral blood lymphocytes during the early post-transplant period were compared between the auxiliary and living donor liver transplantation groups to identify differences.

    Time frame: within 3 months after liver transplantation

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07275008
Lead sponsor
Zhi-Jun Zhu
Responsible party
Zhi-Jun Zhu (Professor, Beijing Friendship Hospital) — Sponsor-investigator
First posted
Dec 10, 2025
Start date
Dec 1, 2025 (estimated)
Primary completion
Dec 31, 2028 (estimated)
Completion
Dec 31, 2029 (estimated)
Last update
Dec 10, 2025

Study contacts

Bin Li
Contact
libin_2024@163.com
+8619935943688

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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