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Active, not recruitingNCT07274306AMIGOUpdated Dec 10, 2025

Incidence, Treatment and Outcome After Acute Mesenteric Ischemia in the Region of Västra Götaland, 2000-2023.

An observational study in Mesenteric Artery Ischemia, sponsored by Sahlgrenska University Hospital. Active, not recruiting at 2 sites in Sweden. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-12-10.

Sponsored by Sahlgrenska University Hospital · Observational

From the registry’s dates

  • Primary completion was expected by Dec 2025, 11 months ago, but the record still lists the study as active, not recruiting.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
2,446
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this retrospective observational study is to describe the incidence and outcome of patients diagnosed with acute mesenteric ischemia (AMI) in the Västra Götaland region of Sweden between 2000-2023. The main questions it aims to answer are:

  • What was the observed incidence and outcome, and how did it change during the time period?
  • How did socioeconomic factors influence incidence and outcome of AMI?
  • What main surgical approaches were selected for these patients?
  • What was the distribution of anticoagulant use in the cohort, and what effect did the introduction of new oral anticoagulants (NOAC) have on incidence and mortality in AMI?
  • What was the prevalence of Short Bowel Syndrome (SBS) after surgical intervention?

Participants were obtained from the regional diagnosis registry. Additional datapoints were obtained from the Swedish statistics bureau and pharmaceutical registers.

02

Conditions studied

  • Mesenteric Artery Ischemia

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Keywords

  • Acute mesenteric ischemia
  • Mesenteric ischemia
  • Intestinal ischemia
  • Population-based cohort
  • Epidemiology
  • Incidence
  • Mortality
  • Mesenteric arterial occlusion
  • Sweden / Västra Götaland
03

In context

Mesenteric Ischemia

40 studies on the registry are indexed under Mesenteric Ischemia; 14 are open to participants now.

This study's enrollment of 2,446 is above the median of 154 across 26 observational studies indexed under Mesenteric Ischemia.

Browse Mesenteric Ischemia studies →

Lead sponsor

Sahlgrenska University Hospital is the lead sponsor of 263 studies on the registry; 68 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Inhabitants of the Västra Götaland region in Sweden.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • all patients discharged from hospital with acute mesenteric ischemia (ICD K55.0 and K55.9)

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
2,446 participants (actual)
Patient registry
No

Groups and cohorts

  • VG Region patients with AMI diagnosis 2000-2023

    A cohort of all patients who were discharged with the diagnosis acute mesenteric ischemia (ICD-10: K55.0 or K55.9) in the Västra Götaland region of Sweden between 2000-01-01 and 2023-12-31.

06

What researchers measure

Primary outcomes

  1. Incidence of acute mesenteric ischemia

    Annual incidence rate of acute mesenteric ischemia per 100,000 person-years in the Västra Götaland region.

    Time frame: Year 2000-2023

  2. Mortality from acute mesenteric ischemia

    All-cause mortality within up to 1 year of AMI diagnosis.

    Time frame: 30 days, 90 days, 1 year.

Secondary outcomes

  1. Temporal trends in incidence and mortality

    Change over time in incidence and mortality, including before and after introduction of non-vitamin K antagonist oral anticoagulants (NOACs).

    Time frame: Year 2000-2023

  2. Socioeconomic determinants of incidence and outcome

    Association between SES indicators (income, education, immigration status, geographic distance to care) and risk of AMI or mortality.

    Time frame: Year 2000-2023

  3. Surgical management strategy

    Proportion of patients undergoing bowel resection, revascularization (open or endovascular), or non-operative management.

    Time frame: Year 2000-2023

  4. Prevalence of Short Bowel Syndrome (SBS)

    Number and percentage of patients developing SBS (ICD-10 K91.2 and K90.8) after AMI.

    Time frame: Within 1 year of surgical intervention

  5. Anticoagulant use patterns

    Proportion of patients using vitamin-K antagonists, NOACs, antiplatelet therapy, or no anticoagulation; association with incidence and survival.

    Time frame: At AMI diagnosis; trends from 2000-2023

07

Study locations

2 sites
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be shared. Due to Swedish data protection legislation and ethical restrictions, the de-identified dataset cannot be made publicly available. Only aggregated results will be published.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07274306
Collaborators
Gothia Forum - Center for Clinical Trial, Göteborg University
Responsible party
Hanna de la Croix (MD, PhD, Sahlgrenska University Hospital) — Principal investigator
First posted
Dec 10, 2025
Start date
Feb 24, 2025
Primary completion
Dec 2025 (estimated)
Completion
Jan 2026 (estimated)
Last update
Dec 10, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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