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CompletedNCT07256847Updated Dec 1, 2025

Effect of 6-Week High Intensity Interval Training on VO2max, Physical Competence and Sleep Quality in Sedentary Male University Students

An interventional study of High intensity interval training in Sedentary Students and University Students, sponsored by Ma Ruisi. Completed at 1 site in Hong Kong. Open to male participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-01.

Sponsored by Ma Ruisi · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 4 months after the study started (first participant enrolled Jul 2024, registered Nov 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
56
Allocation
Randomized
Ages
18 Years and older
Sex
Male
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Study summary

This study aims to investigate the effects of a 6-week high-intensity interval training (HIIT) intervention on physical fitness, cardiorespiratory capacity (VO2max), and sleep quality among sedentary male college students. Through a randomized controlled trial, we seek to examine whether HIIT, as a time-efficient exercise modality, can effectively improve these health-related outcomes in young adults who maintain predominantly sedentary lifestyles. This research will provide evidence-based insights into the effectiveness of HIIT as a potential intervention strategy to address the physical and physiological consequences of prolonged sitting behavior among university students.

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Conditions studied

  • Sedentary Students
  • University Students
03

In context

Lead sponsor

Ma Ruisi is the lead sponsor of 2 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  1. university students;
  2. daily sedentary time > 8 hours;
  3. healthy individuals who are capable of physical tests or HIIT;
  4. no regular exercise habits;
  5. can understand English or Chinese.

Exclusion criteria

Exclusion Criteria:

  1. self-reported history of neurological, psychiatric, or medical diseases;
  2. current intake of medications and/or recreational drugs that could affect the central nervous system and/or the ability to learn.
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
56 participants (actual)

Study arms

  • Experimental
    High-intensity interval training (HIIT) group

    A 6-week HIIT exercise plan (running). Duration: Each session consists of 10 x 1-minute high-intensity bouts interspersed with 10 x 1-minute recovery periods. Adding the 3-minute warmup and 3-minute cool-down, each session totals approximately 26 minutes. This protocol is followed for 6 weeks. Intensity: High-intensity bouts are performed at 80-90% of HRmax (RPE 15-18). Recovery periods are at 40-50% of HRmax (RPE 11-13). Warm-up and cool-down are at 50% HRmax (RPE 11-13). Modality: Running, jogging, or brisk walking, either on a treadmill or outdoors. Supervision: The first three sessions are supervised in a laboratory setting. Subsequent sessions are unsupervised and performed at home with heart rate monitoring and remote data tracking via Polar Flow for Coach.

    Other: High intensity interval training

  • No intervention
    Control

    Keep the usual life style without intervention.

Interventions

  • OtherHigh intensity interval training

    A 6-week HIIT exercise plan (running). Duration: Each session consists of 10 x 1-minute high-intensity bouts interspersed with 10 x 1-minute recovery periods. Adding the 3-minute warmup and 3-minute cool-down, each session totals approximately 26 minutes. This protocol is followed for 6 weeks. Intensity: High-intensity bouts are performed at 80-90% of HRmax (RPE 15-18). Recovery periods are at 40-50% of HRmax (RPE 11-13). Warm-up and cool-down are at 50% HRmax (RPE 11-13). Modality: Running, jogging, or brisk walking, either on a treadmill or outdoors. Supervision: The first three sessions are supervised in a laboratory setting. Subsequent sessions are unsupervised and performed at home with heart rate monitoring and remote data tracking via Polar Flow for Coach.

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What researchers measure

Primary outcomes

  1. VO2max

    Progressive Aerobic Cardiovascular Endurance Run 20-m (measured in laps)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  2. Sleep Quality

    Pittsburgh Sleep Quality Index (PSQI) (scored from 0 to 21, with higher scores indicating worse sleep quality)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  3. Handgrip

    Handgrip dynamometer (measured in kilograms)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  4. Core strength

    Plank test (measured in second)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  5. Balance

    Unipedal stance test (measured in second)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  6. Agility

    Agility T-test (measured in second)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  7. Flexibility

    Sit and Reach Test

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  8. Body composition (measured in centimeter)

    Bioelectrical impedance analysis (BIA) device (MC-780MA)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

Other outcomes

  1. Carbohydrate Intake

    Daily carbohydrate consumption measured by validated 3-day food diary (measured in grams/day)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  2. Fat Intake

    Daily fat consumption measured by a validated 3-day food diary (measured in grams/day)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  3. Protein Intake

    Daily protein consumption measured by a validated 3-day food diary (measured in grams/day)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

  4. Physical Activity Level

    International Physical Activity Questionnaire (IPAQ) long form (measured in MET-minutes/week, range: 0 to no upper limit, with higher scores indicating higher levels of physical activity)

    Time frame: Baseline (pre-intervention) and immediately after 6-week intervention completion

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Study locations

1 site
  • SSPE, The Chinese University of Hong Kong
    Hong Kong, None Selected, Hong Kong
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References and documents

Publications

  • Song X, Cui X, Su W, Shang X, Tao M, Wang J, Liu C, Sun Y, Yun H. Comparative effects of high-intensity interval training and moderate-intensity continuous training on weight and metabolic health in college students with obesity. Sci Rep. 2024 Jul 17;14(1):16558. doi: 10.1038/s41598-024-67331-z. PubMed 39019997 ↗
  • Eather N, Riley N, Miller A, Smith V, Poole A, Vincze L, Morgan PJ, Lubans DR. Efficacy and feasibility of HIIT training for university students: The Uni-HIIT RCT. J Sci Med Sport. 2019 May;22(5):596-601. doi: 10.1016/j.jsams.2018.11.016. Epub 2018 Nov 24. PubMed 30509862 ↗
  • Tang D, Gou P, Liu S, Zhang X, Li D, Liu J. Effects of unsupervised campus HIIT on fitness and sleep in sedentary male students: a randomized controlled trial. BMC Public Health. 2026 Apr 9;26(1):1635. doi: 10.1186/s12889-026-27310-7. PubMed 41957758 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 1, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07256847
Lead sponsor
Ma Ruisi
Responsible party
Ma Ruisi (Co-Investigator, Jinan University Guangzhou) — Sponsor-investigator
First posted
Dec 1, 2025
Start date
Jul 1, 2024
Primary completion
Dec 31, 2024
Completion
Jan 31, 2025
Last update
Dec 1, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.

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