An observational study in Pain, sponsored by Bahçeşehir University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-05-26.
Sponsored by Bahçeşehir University · Observational
Living liver donor hepatectomy at our institution routinely includes ultrasound-guided interfascial plane blocks as part of postoperative analgesia. Although these blocks have become increasingly used in donor hepatectomy, their cutaneous sensory distributions and block-related dermatomal coverage have not been systematically evaluated, with only anecdotal reports available in the literature.
This prospective observational study aims to assess both the sensory blockade patterns and the early postoperative analgesic performance of interfascial plane blocks administered to living liver donors. Following surgery, all consenting donors receive the institution's standard block protocol. Cutaneous sensory mapping is performed in the post-anesthesia care unit (PACU) at the second postoperative hour. Pain intensity and analgesic requirements within the first 24 hours are also recorded.
The study is designed to provide objective data on the dermatomal coverage and postoperative analgesic effects of contemporary ultrasound-guided interfascial plane blocks used in living liver donor surgery.
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The study population consists of adult living liver donors undergoing elective donor hepatectomy at a tertiary care center. All participants receive ultrasound-guided interfascial plane blocks as part of the institution's routine postoperative analgesia protocol. Eligible donors are aged 18 to 65 years, classified as ASA physical status I-II, and able to cooperate with postoperative cutaneous sensory mapping procedures. Individuals with contraindications to regional anesthesia, conditions preventing accurate sensory assessment, or those who decline participation are excluded.
Exclusion Criteria:
Ultrasound-guided interfascial plane blocks are administered at the end of surgery. Block selection and needle entry points are determined according to the surgical incision line and the location of abdominal drains. All blocks are performed under real-time ultrasound guidance using the institution's standardized protocol.
Intravenous patient-controlled analgesia is initiated in the postoperative period according to the institution's standard protocol. PCA settings, opioid type, basal infusion (if applicable), and bolus doses follow routine clinical practice and are recorded for analysis. PCA use during the first 24 hours is monitored to assess postoperative analgesic requirements.
Cutaneous sensory mapping is performed in the post-anesthesia care unit (PACU) at the second postoperative hour. Sensory blockade is assessed using a standardized pinprick test applied radially from medial to lateral directions. The borders of the blocked and unblocked regions are marked on the skin using a UV-visible dermatographic pen. Mapping is conducted over the mid-abdominal and lateral abdominal regions, and the total cutaneous coverage areas are subsequently calculated for analysis.
Cutaneous sensory block area mapping for different regional anesthesia techniques in liver donor surgery
The cutaneous sensory block area produced by the regional anesthesia technique will be evaluated at the 120th minute post-block using a standardized pinprick test. Sensory borders will be identified radially and marked on the skin with a UV-visible marker. Each mapped region will be photographed with a calibrated reference scale placed on the skin. These images will be processed using a predefined digital template to calculate the total blocked surface area in square centimeters. The resulting measurements will be used to characterize the sensory distribution of the interfascial plane blocks in living liver donors.
Time frame: At 120 minutes after block administration in the post-anesthesia care unit (PACU).
Plan to share: No
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Bahçeşehir University