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CompletedNCT07249177Updated Nov 25, 2025

Upper Extremity Functional Index in Carpal Tunnel Syndrome

An observational study in Carpal Tunnel Syndrome (CTS) and Upper Extremity Function, sponsored by Pamukkale University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-11-25.

Sponsored by Pamukkale University · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
101
Ages
18 Years to 65 Years
Sex
All
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Study summary

The aim of this study was to investigate the validity and reliability of the Upper Extremity Functional Index in patients with carpal tunnel syndrome. This cross-sectional study included 101 patients diagnosed with carpal tunnel syndrome at a university hospital. Patients were administered the Upper Extremity Functional Index, Michigan Hand Outcomes Questionnaire, and Boston Carpal Tunnel Questionnaire surveys. Test-retest reliability, internal consistency, and construct validity of the Upper Extremity Fuctional Index were evaluated.

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Conditions studied

  • Carpal Tunnel Syndrome (CTS)
  • Upper Extremity Function

Keywords

  • psychometrics
  • carpal tunnel syndrome
  • outcome measures
  • upper extremity functional index
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In context

Carpal Tunnel Syndrome

589 studies on the registry are indexed under Carpal Tunnel Syndrome; 139 are open to participants now.

This study's enrollment of 101 is above the median of 90 across 127 observational studies indexed under Carpal Tunnel Syndrome.

Browse Carpal Tunnel Syndrome studies →

Lead sponsor

Pamukkale University is the lead sponsor of 331 studies on the registry; 61 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

This study included patients aged 18-65 years who were diagnosed with carpal tunnel syndrome after visiting the neurology outpatient clinic of a university hospital, who volunteered, who had no history of other trauma, disease, or surgery in the affected limb, and who had no communication difficulties. The patients were included before starting any conservative or surgical treatment programme.

Inclusion criteria

  • To be diagnosed with carpal tunnel syndrome, to be a volunteer, and to be between the ages of 18 and 65 years.

Exclusion criteria

Exclusion Criteria:

  • no history of other trauma, disease or surgery in the affected limb and difficulty communicating
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Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
101 participants (actual)
Target follow-up
2 Weeks
Patient registry
Yes

Groups and cohorts

  • Patients aged 18-65 years diagnosed with carpal tunnel syndrome.

    Other: Questionnaire

Interventions

  • OtherQuestionnaire

    The Upper Extremity Functional Index (at the first session and after 2 weeks), the Michigan Hand Outcomes Questionnaire and the Boston Carpal Tunnel Questionnaire were administered to patients using a face-to-face assessment method.

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What researchers measure

Primary outcomes

  1. Upper Extremity Functional Index

    It is a 20-item scale scored using a 4-point Likert scale (0 = Extremely difficult/I cannot do it, 4 = I do not experience any difficulty). The patient scores between 0 and 80, and it is recommended that the total score be used in studies. A high score indicates that the patient has good upper extremity function.

    Time frame: The questionnaire was administered at baseline (after diagnosis of carpal tunnel syndrome) and 15 days after the baseline assessment.

  2. Michigan Hand Outcomes Questionnaire

    This questionnaire evaluates the functionality of the hand and consists of 63 questions in total. Each question is scored between 1-5 and the score of each section varies between 0-100. High total score indicates high satisfaction.

    Time frame: The questionnaire was administered at baseline (after diagnosis of carpal tunnel syndrome)

  3. Boston Carpal Tunnel Questionnaire

    It has been developed to assess the severity of symptoms and functional status in patients with carpal tunnel syndrome. The symptom severity scale consists of 11 questions, while the functional status scale consists of 8 questions. Each question is scored between 1 and 5. A higher symptom severity or functional status score indicates worse symptoms or functional impairment.

    Time frame: The questionnaire was administered at baseline (after diagnosis of carpal tunnel syndrome)

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Study locations

1 site
  • Pamukkale University
    Denizli, 20170, Turkey (Türkiye)
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References and documents

Publications

  • Aytar A, Yuruk ZO, Tuzun EH, Baltaci G, Karatas M, Eker L. The Upper Extremity Functional Index (UEFI): cross-cultural adaptation, reliability, and validity of the Turkish version. J Back Musculoskelet Rehabil. 2015;28(3):489-95. doi: 10.3233/BMR-140545. PubMed 25322741 ↗
  • Sousa RL, Moraes VY, Zobiole AF, Nakachima LR, Belloti JC. Diagnostic criteria and outcome measures in randomized clinical trials on carpal tunnel syndrome: a systematic review. Sao Paulo Med J. 2023 Apr 17;141(6):e2022086. doi: 10.1590/1516-3180.2022.0086.07022023. eCollection 2023. PubMed 37075455 ↗

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 25, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07249177
Lead sponsor
Pamukkale University
Responsible party
UMUT ERASLAN (Assistant Professor, Pamukkale University) — Principal investigator
First posted
Nov 25, 2025
Start date
Jun 28, 2021
Primary completion
Nov 18, 2022
Completion
Nov 18, 2022
Last update
Nov 25, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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