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RecruitingNCT07246954Updated Sep 25, 2026

A Chaplain-clinician Led Spiritual Care (PEACE) Intervention on Spiritual/Religious Beliefs Related to Medical Care in Patients With Advanced Cancer: a Pilot Clinical Trial

An interventional study of Peace Intervention and Usual Care in Spiritual Care and Advanced Cancer, sponsored by M.D. Anderson Cancer Center. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-25.

Sponsored by M.D. Anderson Cancer Center · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Started Dec 2025; still recruiting 9 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

To examine the feasibility and acceptability of chaplain-clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer.

Read the detailed description

Primary Objectives

(Phase 1): To examine the feasibility and acceptability of a Chaplain-Clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer admitted to a comprehensive cancer center in a single-arm pilot trial. Evaluation of feasibility will be per ≥70% participation in all sessions.

Acceptability will be assessed as ≥70% reporting satisfaction and ≥70% recommending PEACE intervention to others at the post-treatment assessment.

(Phase 2): To examine the within-group change in the influence of spiritual/religious beliefs on medical care (Question 2 in the Religious Beliefs in End-of-Life Medical Care [RBEC] tool: I will accept every possible medical treatment because my faith tells me to do everything I can to stay alive longer) from baseline to post-intervention assessments at 2 + 1 days in participants who participate in the PEACE intervention group and the usual care group.

02

Conditions studied

  • Spiritual Care
  • Advanced Cancer
03

In context

Lead sponsor

M.D. Anderson Cancer Center is the lead sponsor of 2,999 studies on the registry; 581 are open to participants now.

Of its 599 completed or terminated interventional studies of FDA-regulated products, 402 (67%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

Eligibility Criteria

  1. Participants with advanced cancer (locally advanced, metastatic, recurrent, or incurable) seen by the participant supportive/palliative care mobile team at MD Anderson Cancer Center.
  2. Respond "somewhat to A great deal" to the question in the RBEC questionnaire "I will accept every possible medical treatment because my faith tells me to do everything I can to stay alive longer".
  3. Participant s aged 18 years or over.
  4. Karnofsky performance status ≥30% at time of inclusion into study.
  5. Normal cognitive status as determined by the supportive care clinicians based on the ability to understand the nature of the study and consent process.
  6. Only English-speaking, as determined by their ability to understand the informed consent, the intervention, and the assessment tools.
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    Phase 1

    Patients will participate in two PEACE intervention sessions, which will last 30-60 minutes each.

    Other: Peace Intervention

  • Experimental
    Phase 2

    Usual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team

    Other: Peace Intervention · Other: Usual Care

Interventions

  • OtherPeace Intervention

    Patients will participate in two PEACE intervention sessions, which will last 30-60 minutes each.

  • OtherUsual Care

    Usual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team.

06

What researchers measure

Primary outcomes

  1. RBEC Questionnaire

    Time frame: Through study completion; an average of 1 year

07

Study locations

1 of 1 sites recruiting
  • MD Anderson Cancer Center
    Houston, Texas 77030, United States
    Recruiting
08

References and documents

09

Updates

1 registry update since Sep 25, 2026
Minor edits
Nothing that changes what the study is or who can join. Edited: verification date
1 update, last Sep 25, 2026
Show all 1 update
  1. Sep 25, 2026
    Minor edits only
    + 1 other change: verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07246954
Lead sponsor
M.D. Anderson Cancer Center
Responsible party
Sponsor
First posted
Nov 24, 2025
Start date
Dec 22, 2025
Primary completion
Jan 1, 2027 (estimated)
Completion
Jan 1, 2029 (estimated)
Last update
Sep 25, 2026

Study contacts

Marvin Delgado Guay, MD
Contact
marvin.delgado@mdanderson.org
713-745-8190
Marvin Delgado Guay, MD
principal investigator · M.D. Anderson Cancer Center

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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