An observational study in Lipedema, sponsored by Istanbul Physical Medicine Rehabilitation Training and Research Hospital. Completed at 1 site in Turkey (Türkiye). Open to female participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-11-20.
Sponsored by Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Observational
Among 41 studies in Lipedema with a site in Turkey — 18 open to participants now, 19 under way, none of them phase 3. Lipedema · Turkey.
Among the 41 studies in Lipedema with a site in Turkey, this one is the 17th largest by enrollment of the 27 observational ones that give a count, is one of 9 that started in 2025, is one of 27 observational ones, and was the 17th registered.
85 studies on the registry are indexed under Lipedema; 32 are open to participants now.
This study's enrollment of 60 is below the median of 90 across 42 observational studies indexed under Lipedema.
Browse Lipedema studies →18 of the 41 studies in Lipedema with a site in Turkey are open now, in 1 country. Each count lists the studies.
Of the 19 Lipedema studies recruiting now, 3 (16%) set no upper age limit and 16 (84%) stop at 75 or younger; 0 take children under 18; 4 take healthy volunteers.
This study: 18 Years to 75 Years · female.
The full table on the hub →41 studies; the count open now beside each. This study's row is marked.
First in 2019; this study’s year is marked. 9 started in 2025.
Median enrollment 37 across the 14 interventional studies, 76 across the 27 observational. Of the 22 that completed or were terminated, 0 (0%) have results posted.
None of the 41 has an industry lead sponsor. The 10 most frequent:
Istanbul Physical Medicine Rehabilitation Training and Research Hospital is the lead sponsor of 123 studies on the registry; 26 are open to participants now.
Istanbul Physical Medicine Rehabilitation Training and Research Hospital has 3 studies filed under Lipedema — fewer than ten, so there is no comparison to draw.
10 of the studies in Lipedema with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07878299Sultan Abdulhamid Han Training and Research Hospital, Istanbul, TurkeyComparison of Segmental Body Composition Characteristics in Lipedema and Obesity | 2026-11-20 |
| NCT07683559Atlas UniversityExtracorporeal Shock Wave Therapy in Patients With Lipedema | 2026-12-01 |
| NCT07919574Hatice Zehra FERHATLAREffectiveness of Kinesio Taping as an Adjunct to Conservative Treatment in Women With Lipedema | 2027-01-15 |
| NCT07803926Merve SEVINC GUNDUZManual and Self-Lymphatic Drainage Combined With Exercise in Women With Lipedema | 2027-01-20 |
| NCT07468097Marmara UniversityThe Impact of Metabolic Status on Pain and Central Sensitization in Women With Lipedema: A Cross-Sectional Observational Study | 2027-02-01 |
Among the 41 studies in Lipedema with a site in Turkey, from their registry updates:
This cross-sectional study will include women aged 18-75 with clinically diagnosed lipedema and healthy controls. Sociodemographic and clinical data will be collected, and participants will complete the Central Sensitization Inventory (CSI), Visual Analog Scale (VAS), Hospital Anxiety and Depression Scale (HADS), and Pain Catastrophizing Scale (PCS). Pain pressure thresholds (PPT) will be assessed using a digital algometer at the middle deltoid, lateral thigh, and medial knee, with three measurements taken at each site and the average recorded.
-Patients with and without lipedema
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients with lipedema
Patients without lipedema
Central Sensitization Inventory (CSI)
The CSI assesses symptoms related to central sensitization, such as widespread pain, fatigue, and sleep disturbance. Scores range from 0 to 100, with higher values indicating a greater degree of central sensitization.
Time frame: Baseline
Pain Intensity (Visual Analog Scale - VAS)
Pain intensity will be rated on a 10-cm scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores reflect greater perceived pain severity.
Time frame: Baseline
Hospital Anxiety and Depression Scale - Anxiety Subscale (HADS-A):
The HADS-A assesses anxiety symptoms in non-psychiatric populations. Scores range from 0 to 21; higher scores indicate greater anxiety severity.
Time frame: Baseline
Hospital Anxiety and Depression Scale - Depression Subscale (HADS-D)
The HADS-D evaluates depressive symptoms, with scores ranging from 0 to 21. Higher scores indicate more severe depressive symptoms.
Time frame: Baseline
Pain Catastrophizing Scale (PCS):
he PCS measures negative cognitive and emotional responses to pain. Scores range from 0 to 52, with higher scores indicating greater pain catastrophizing.
Time frame: Baseline
Pain Pressure Threshold (PPT):
PPT will be measured using a digital algometer at the middle deltoid, lateral thigh, and medial knee. Lower values indicate greater pain sensitivity.
Time frame: Baseline
Ran from Oct 2025 to primary completion in Nov 2025, 1 month.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.
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