An observational study in Primary Dysmenorrhea, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to female participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-12.
Sponsored by Cairo University · Observational
The purpose of the study is to assess knee joint position sense, pain and dynamic balance in female with primary dysmenorrhea.
Dysmenorrhea is a common condition that typically occurs on its own rather than as a result of pelvic disease. It affects between 50% and 90% of adolescent girls and women of reproductive age and is a major reason for missed days from school or work.
Among the various menstrual disturbances observed, dysmenorrhea was notably prevalent among adolescents and significantly impacted their daily activities. Early diagnosis and awareness of menstrual issues are crucial, as they not only emphasize the need for health education initiatives but also assist in selecting suitable treatments, thereby reducing the adverse effects of these disturbances on adolescents' lives.
However, there is a significant gap in the literature about the effect of Primary dysmenorrhea on knee joint position sense, pain and dynamic balance in young adult female So this study aims to investigate this effect and provide evidence based information in the field of physical therapy.
Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Sixty-two healthy female university students will participate in this study. They will be selected randomly from faculty of physical therapy, Cairo University.
Exclusion Criteria:
They have no or mild primary dysmenorrhea.
Other: No intervention
They have moderate and sever primary dysmenorrhea.
Other: No intervention
No intervention
Overall Stability Index (OSI) . Antero-posterior stability index score (APSI) . Medio lateral stability index score (MLSI) . Over all stability index score (OASI)
The Overall Stability Index (OSI) is the primary measure of dynamic postural control obtained from the balance assessment system. It reflects the standard deviation of the participant's sway from the platform's center across both the medial-lateral and anterior-posterior directions. Higher OSI values indicate greater instability and poorer balance performance. As an integrated measure of sway variability, the OSI is considered the most comprehensive indicator of overall balance ability and is commonly used to evaluate changes in postural control in response to therapeutic interventions.
Time frame: at first and fourth menstrual days
Medial-Lateral Stability Index (MLSI)
The Medial-Lateral Stability Index (MLSI) quantifies the degree of side-to-side sway during balance testing. It represents the standard deviation of medial-lateral movement from the platform's center point, providing a directional measure of postural stability. Elevated MLSI scores reflect increased lateral instability, which may be associated with impaired neuromuscular control or deficits in weight-shifting ability. This variable is useful for identifying balance impairments that predominantly affect frontal plane stability.
Time frame: at first and fourth menstrual days
Anterior-Posterior Stability Index (APSI)
The Anterior-Posterior Stability Index (APSI) measures front-to-back sway during dynamic balance assessment. Calculated as the standard deviation of anterior-posterior deviations from the center of the platform, the APSI provides insight into sagittal plane stability. Higher APSI values indicate greater instability and reduced capacity to control forward and backward movements. This index is important for evaluating postural control related to gait, stepping, and activities requiring controlled anterior or posterior shifts in the center of gravity.
Time frame: at first and fourth menstrual days
knee joint position sense
using active knee position sense test by universal goniometer.
Time frame: at first and fourth menstrual days
knee joint pain
It will be assessed using the Visual analog scale (VAS) for all females in both groups. They will score their level of pain from 1-10, with higher scores indicating more severe pain. It is valid and reliable in pain assessment
Time frame: at first and fourth menstrual days
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Cairo University