CClinicalTrials.gg
CompletedNCT07228507Video_REDsUpdated Nov 17, 2025

Video Intervention of Relative Energy Deficiency in Sport

An interventional study of Behavioral: Educational Program on Female Athlete Triad and Relative Energy Deficiency in Sport (RED-S) in Female Athlete Triad, Relative Energy Deficiency in Sport and Knowledge, sponsored by University of the Basque Country (UPV/EHU). Completed at 1 site in Spain. Per ClinicalTrials.gov, last updated 2025-11-17.

Sponsored by University of the Basque Country (UPV/EHU) · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
200
Allocation
Randomized
Sex
All
01

Study summary

The Female and Male Athlete Triad (Triad) and Relative Energy Deficiency in Sport (REDs) are multifactorial conditions often under-recognized by healthcare professionals. Improving provider awareness is essential for early detection and multidisciplinary management in sport medicine. Thus, the objective was to assess the effectiveness of a brief online educational video in improving knowledge, attitudes, and perceived confidence toward the Triad and REDs among Spanish healthcare professionals.

Read the detailed description

The objective was to assess the effectiveness of a brief online educational video in improving knowledge, attitudes, and perceived confidence toward the Triad and REDs among Spanish healthcare professionals.

Design: Randomized controlled educational trial. A total of 200 Spanish healthcare professionals (physicians, nurses, and physiotherapists) were randomized 1:1 into an intervention group (VG) and a control group (CG). The VG received access to an 18-minute YouTube-based educational video titled "Triad of the Female Athlete and RED-S". The CG did not have access to the video until the study was completed. Both completed a validated 16-question questionnaire before and after the intervention.

The Primary Outcome Measure was the change in knowledge score about the Female/Male Athlete Triad and REDs. Secondary outcomes included questions from the definition group (questions 1 and 3), low energy availability group (questions 2, 4, 5, 10, 14, 15 and 16), the menstrual health group (questions 6,9,11 and 13) and the bone health group (questions 7,8 and 12)

Descriptive analyses were conducted to determine means, standard deviations, frequencies, and percentages. A two-way repeated-measures ANOVA was performed after verifying the statistical assumptions required for this methodology. Outliers were examined using the first and third quartiles and the interquartile range. Participants with a total score ≤4 were excluded from the analysis to preserve the reliability and validity of the data and to ensure that statistical analyses reflected only responses with adequate informational content consistent with the study conditions. Data normality was assessed through Q-Q plots and the Shapiro-Wilk test. The effects of the group factor (VG vs. CG), the time factor (pre- vs. post-test), and their interaction were analysed, considering a 95% confidence interval (p ≤ 0.05).

Knowledge Questions

  1. What do you consider to be the three components of the Female Athlete Triad?
  2. Low energy availability in a person occurs when the energy to maintain the functions required by the human body to preserve health and optimal performance is insufficient.
  3. What is the main factor that would cause REDs?
  4. Low energy availability could be associated with a decrease in carbohydrate intake.
  5. There may be low energy availability without changes in weight or body mass index.
  6. Menarche in adolescents after the age of 15 is normal if they engage in intense physical activity.
  7. At what age does peak bone mineral density occur in women?
  8. Osteopenia in adolescent girls or young adult women can be reversed if, in adulthood, they reduce the intensity or volume of their physical activity.
  9. In a physically active woman, secondary amenorrhea can be considered normal if she engages in intense sport.
  10. Menstrual disorders in physically active women are a risk factor for having low bone mineral density.
  11. Low energy availability can cause secondary amenorrhea in physically active women.
  12. In physically active women, menstrual cycle alterations or amenorrhea are indicators of intense training.
  13. In physically active women, stress fractures may occur at a higher rate in women with prolonged amenorrhea than in eumenorrheic women.
  14. Low energy availability can affect an athlete's recovery.
  15. Low energy availability can increase performance (strength, speed, power).
  16. After performing intense exercise, the basis of caloric intake should be...
02

Conditions studied

  • Female Athlete Triad
  • Relative Energy Deficiency in Sport
  • Knowledge

Keywords

  • Knowledge
  • Female Athlete Triad
  • Relative Energy Deficiency in sport
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Registered in a health professional association in Spain (medicine, nursing, or physiotherapy).
  • Voluntary participation and completion of the baseline questionnaire.
  • Consent to provide an email address for communication and randomization

Exclusion criteria

Exclusion Criteria:

  • Not to be registered in a health professional association in Spain (medicine, nursing, or physiotherapy).
  • Incomplete questionnaire responses.
  • Total score ≤4 in the pre-test, to preserve data reliability and validity.
04

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
200 participants (actual)

Study arms

  • Experimental
    Educational video

    Participants attend an educational video and complete the questionnaire pre- and post-intervention.

    Other: Behavioral: Educational Program on Female Athlete Triad and Relative Energy Deficiency in Sport (RED-S)

  • No intervention
    Control

    Participants complete the same questionnaire at baseline and follow-up without receiving the educational video

Interventions

  • OtherBehavioral: Educational Program on Female Athlete Triad and Relative Energy Deficiency in Sport (RED-S)

    Participants in the intervention arm attended an educational session designed to improve knowledge about the Female Athlete Triad and REDs, focusing on definition, low energy availability, menstrual function, and bone health.

05

What researchers measure

Primary outcomes

  1. Change in knowledge score (mean proportion of correct answers) from baseline to post-intervention.

    Knowledge assessed using a 16-item questionnaire on the Female Athlete Triad and Relative Energy Deficiency in sport. Each item scored 0-1 and the outcome is a score 0-16 points. A higher scores means better knowledge.

    Time frame: Baseline and 4 weeks after intervention

Secondary outcomes

  1. Change in definition questions group

    Correct answers from the definition questions group. Each question is scored 0-1 and the outcome is a score 0-2 points. A higher scores indicate greater knowledge.

    Time frame: Baseline and 4 weeks after intervention

  2. Change in low energy availability questions group

    Correct answers from the low energy availability questions group. Each question is scored 0-1 and the outcome is a score 0-7 points A higher scores indicate greater knowledge.

    Time frame: Baseline and 4 weeks after intervention

  3. Change in menstrual questions group

    Correct answers from the menstrual questions group. Each question is scored 0-1 and the outcome is a score 0-4 points. A higher scores indicate greater knowledge.

    Time frame: Baseline and 4 weeks after intervention

  4. Change in bone health questions group

    Correct answers from the bone questions group. Each question is scored 0-1 and the outcome is a score 0-3 points. A higher scores indicate greater knowledge.

    Time frame: Baseline and 4 weeks after intervention

06

Study locations

1 site
  • Universidad del Pais Vasco
    Leioa, Basque Country 48940, Spain
07

References and documents

Publications

  • Tam R, Beck KL, Manore MM, Gifford J, Flood VM, O'Connor H. Effectiveness of Education Interventions Designed to Improve Nutrition Knowledge in Athletes: A Systematic Review. Sports Med. 2019 Nov;49(11):1769-1786. doi: 10.1007/s40279-019-01157-y. PubMed 31372860 ↗
  • Verhoef SJ, Wielink MC, Achterberg EA, Bongers MY, Goossens SMTA. Knowledge on relative energy deficiency in sport among physiotherapists and physicians. Eur J Sport Sci. 2024 Jan 30;24(1):156-63. doi: 10.1002/ejsc.12026. PMCID: PMC11235195.

Individual participant data

Plan to share: No

08

Registry details

Key details

Study ID
NCT07228507
Lead sponsor
University of the Basque Country (UPV/EHU)
Responsible party
Susana Gil (Principal Investigator, University of the Basque Country (UPV/EHU)) — Principal investigator
First posted
Nov 14, 2025
Start date
May 30, 2024
Primary completion
Apr 30, 2025
Completion
May 1, 2025
Last update
Nov 17, 2025

Study contacts

Susana M Gil, MD, PhD
principal investigator · University of the Basque Country (UPV/EHU)

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion