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RecruitingNCT07221903LAMUpdated Nov 4, 2025

The Lateral, Anterior, Medial (LAM) Femoral Cutaneous Block: A Case Series Harborview Medical Center, Seattle, WA

An observational study in Regional Anesthesia, Burn and Skin Grafting, sponsored by University of Washington. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-11-04.

Sponsored by University of Washington · Observational

From the registry’s dates

  • Started Oct 2025; still recruiting 11 months later.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
10
Ages
18 Years and older
Sex
All
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Study summary

Skin donor sites in patients undergoing split-thickness skin grafting surgeries can be very painful postoperatively. This site is most often the anterolateral thigh, the pain at which location can traditionally be covered by a fascia iliaca nerve block, although that comes with the disadvantage of losing motor functions in the femoral nerve distribution. The LAM nerve block, which is relatively new, aims to provide analgesia in the distribution of the lateral and anterior femoral cutaneous nerves. In short, this nerve block would decrease the sensation of the anterolateral thigh area without affecting the motor function of the leg. Investigators aim to study the consistency and coverage size of sensation changes by mapping out the area after the block in each patient.

02

Conditions studied

  • Regional Anesthesia
  • Burn
  • Skin Grafting

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03

In context

Burns

719 studies on the registry are indexed under Burns; 145 are open to participants now.

This study's planned enrollment of 10 is below the median of 55 across 135 observational studies indexed under Burns.

Browse Burns studies →

Lead sponsor

University of Washington is the lead sponsor of 1,397 studies on the registry; 225 are open to participants now.

Of its 154 completed or terminated interventional studies of FDA-regulated products, 132 (86%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients 18 years or older who are undergoing skin grafting surgeries

Inclusion criteria

  1. 18 years or older
  2. Scheduled surgery for STSG w/ donor site coming from thigh
  3. Care team requests LAM nerve block
  4. Anticipated postop pain in the cutaneous areas of anterior and lateral thigh

Exclusion criteria

Exclusion Criteria:

  1. Inability to communicate sensation or motor changes in their body
  2. Preexisting sensory or motor deficits in the femoral nerve distribution
  3. Contraindication to the medication used or a peripheral nerve block, such as allergy to amide local anesthetics, severe liver dysfunction, injection site infection etc
  4. Pregnancy
  5. Prisoners
  6. Non-English Speaking/reading
  7. Surgeries with anticipated or actual duration of 6 hours or longer
  8. TBSA 20% or greater
  9. Severe distracting injuries/polytrauma (e.g., large or significant bone fractures)
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
10 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Area of sensory change after nerve block

    Time frame: 20 min after nerve block placement

07

Study locations

1 of 1 sites recruiting
  • Harborview Medical Center
    Seattle, Washington 98104, United States
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07221903
Lead sponsor
University of Washington
Responsible party
Dorothy Wang (Acting Assistant Professor, Department of Anesthesiology and Pain Medicine, University of Washington) — Principal investigator
First posted
Oct 28, 2025
Start date
Oct 22, 2025
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Nov 4, 2025

Study contacts

Adrienne James
Contact
ajames1@uw.edu
206-744-4634
Dorothy Wang, MD, MHA
principal investigator · University of Washington

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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