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RecruitingNCT07218939Updated May 19, 2026

Universal Biospecimen Collection Protocol for Extra Material From Clinical Pulmonary Procedures

An observational study in Pulmonary, sponsored by M.D. Anderson Cancer Center. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-19.

Sponsored by M.D. Anderson Cancer Center · Observational

From the registry’s dates

  • Started Oct 2025; still recruiting 11 months later.
Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
12,000
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this study is to develop a biospecimen collection protocol for unused biospecimens from pulmonary procedures in order to facilitate research across many different areas of pulmonary medicine and mitigate the pulmonary morbidity experienced by patients with cancer.

Read the detailed description

Primary objectives:

To assemble a tissue/blood bank biorepository for laboratory translational research by collecting extra samples of bronchoalveolar lavage, pleural fluid, blood or other residual tissue obtained during normally scheduled clinical procedures for the evaluation of pulmonary toxicity

To collect basic data on patient data and suspected pulmonary toxicity to cross-reference eligible biospecimens

02

Conditions studied

  • Pulmonary
03

In context

Lead sponsor

M.D. Anderson Cancer Center is the lead sponsor of 2,999 studies on the registry; 581 are open to participants now.

Of its 599 completed or terminated interventional studies of FDA-regulated products, 402 (67%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients scheduled for pulmonary procedures in the Cardiopulmonary Center are eligible to be approached for consent and enrollment into this observational biospecimen collection protocol.

Inclusion criteria

All patients over the age of 18, who are seen in the Cardiopulmonary Center and are undergoing pulmonary procedures

Exclusion criteria

Exclusion Criteria:

Pregnant women and prisoners

05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
12,000 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Safety and Adverse Events (AEs)

    Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

    Time frame: Through study completion; an average of 1 year

07

Study locations

1 of 1 sites recruiting
  • The University of Texas M. D. Anderson Cancer Center
    Houston, Texas 77030, United States
    Recruiting
08

References and documents

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 19, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07218939
Lead sponsor
M.D. Anderson Cancer Center
Responsible party
Sponsor
First posted
Oct 21, 2025
Start date
Oct 8, 2025
Primary completion
Dec 1, 2030 (estimated)
Completion
Dec 1, 2032 (estimated)
Last update
May 19, 2026

Study contacts

Ajay Sheshadri, MD
Contact
asheshadri@mdanderson.org
(713) 563-1987
Ajay Sheshadri, MD
principal investigator · M.D. Anderson Cancer Center

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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