ClinicalTrials.gg
CompletedNCT07204405Updated Oct 2, 2025

Haemorrhage From Severe Neck and Facial Injuries - Characteristics, Management and Outcomes

An observational study in Trauma (Including Fractures), Facial Bones Fracture and Neck Injuries, sponsored by Karolinska University Hospital. Completed. Per ClinicalTrials.gov, last updated 2025-10-02.

Primary conditionFacial InjuriesRegistry: Wounds and InjuriesReclassifiedWhy we changed it
Registry
Wounds and Injuries — the first condition term the registry derived for this study.
ClinicalTrials.gg
Facial Injuries
Why
  1. The study's title name Facial Injuries, a narrower term within Wounds and Injuries.
Confidence
High: the new condition is named in the study's own title. Of 46 hand-checked studies reclassified this way, 72% were exactly right and 89% in the right disease family; the registry's first term was right for 4% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Karolinska University Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
15,000
Sex
All
01

Study summary

This is a descriptive observational study of trauma patients admitted to the Trauma Unit at the Karolinska University Hospital Solna, Stockholm, Sweden. Data will be collected from the Karolinska Trauma Registry for all patients from 2015 to 2024. A more detailed dataset will be extracted from the Trauma Registry for all patients with serious facial or neck injuries. For those patients, data will also manually be extracted from their clinical records.

Read the detailed description

Data will be collected from the Karolinska Trauma Registry for all patients from 2015 to 2024. A more detailed dataset will be extracted from the Trauma Registry for all patients with an Abbreviated Injury Scale (AIS) severity score of ≥ 3 for facial or neck injuries. Data will include demographics, injury mechanism, injury type, physiology, treatment and outcome. For those patients with a severe facial or neck injury, data will also manually be extracted from their clinical records regarding prehospital details, initial physiology, injury type, treatment and bleeding.

02

Conditions studied

  • Trauma (Including Fractures)
  • Facial Bones Fracture
  • Neck Injuries

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Keywords

  • Facial injury
  • Neck injury
  • Trauma
  • Bleeding
03

In context

Facial Injuries Reclassified

22 studies on the registry are indexed under Facial Injuries; 5 are open to participants now.

Browse Facial Injuries studies →

Lead sponsor

Karolinska University Hospital is the lead sponsor of 279 studies on the registry; 55 are open to participants now.

Compared within Facial Injuries, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Wounds and Injuries. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients included in the Karolinska Trauma Registry. Those with an AIS>2 for neck or facial injury will be studied in more detail.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients included in the Karolinska Trauma Registry

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
15,000 participants (estimated)
Target follow-up
30 Days
Patient registry
Yes
06

What researchers measure

Primary outcomes

  1. Death from bleeding

    Death from bleeding within 30 days.

    Time frame: 30 days

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jan 2015 to primary completion in Dec 2024, 119 months.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 24, 2025
First posted
Oct 2, 2025
StartActual
Jan 1, 2015
Primary completionActual
Dec 31, 2024
CompletionActual
Jun 1, 2025
Last update
Oct 2, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Oct 2, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07204405
Responsible party
Magnus Hedberg (MD, PhD, Karolinska Institutet) — Principal investigator
First posted
Oct 2, 2025
Start date
Jan 1, 2015
Primary completion
Dec 31, 2024
Completion
Jun 1, 2025
Last update
Oct 2, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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