A Phase 4 interventional study of MEBO Wound Ointment and zinc oxide in Pressure Injury, Pressure Injury Stage 2 and Bedsore, sponsored by King Abdullah Medical City. Recruiting at 2 sites in Saudi Arabia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-09-26.
Sponsored by King Abdullah Medical City · Phase 4, Interventional, and Treatment
randomize control trial to evaluate the efficacy of using zinc oxide versus moist exposed wound ointment in treatment of second stage pressure ulcer.
In this study the subject will be randomized using electronic randomization 1:1 ratio. The randomization list was generated electronically through R using the Random Allocation Rule. The data will be collected using Assessment sheet of patient with second stage pressure ulcer tool. Patients will equally be allocated into 2 groups randomly. The zinc oxide group will receive topical zinc oxide twice every 12 hours daily and patients in the MEBO group will receive topical MEBO ointment twice every 12 daily. Patient will be examined daily till complete healing for the pressure ulcer and maximum one month. The Bates-Jensen Wound Assessment Tool (BWAT) will be used to evaluate wound healing. It is a validated wound assessment tool which is used in many healthcare settings for wound assessment
518 studies on the registry are indexed under Pressure Ulcer; 117 are open to participants now.
This study's planned enrollment of 76 is close to the median of 70 across 395 interventional studies indexed under Pressure Ulcer.
Browse Pressure Ulcer studies →King Abdullah Medical City is the lead sponsor of 5 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
The zinc oxide group will receive topical zinc oxide twice every 12 hours daily
Drug: zinc oxide
patients in the MEBO group will receive topical MEBO ointment twice every 12 daily
Drug: MEBO Wound Ointment
both are used for second pressure ulcer
both are used to treat second degree pressure ulcer but with no superiority
Wound healing
Wound healing will be assessed by using Bates-Jensen Wound Assessment Tool (BWAT) daily for both treatments. (BWAT) consists of 13 items to evaluate wound size, type and depth, Each item is graded on a scale of 1 to 5, where a score of 1 indicates progress toward healing while a score of 5 indicates the absence of healing or wound deterioration. Cumulative BWAT scores vary from 13 to 65
Time frame: 30 days
Recovery time
The duration of treatment will be record at the assessment sheet so Recovery time will be determined from this sheet.
Time frame: 30 days
Documents are hosted by the registry — open the source record to download them.
Plan to share: Undecided — we are still conducting the study after publication we might be interested and ready for sharing the full plan
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King Abdullah Medical City