An interventional study of Resonance Frequency Analysis (RFA) and Bite Force Sensor in Tooth Ankylosis, Cemento-Osseous Dysplasia and Jaw Diseases / Diagnosis, sponsored by Eskisehir Osmangazi University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-09-22.
Sponsored by Eskisehir Osmangazi University · Not applicable, Interventional, and Diagnostic
This study aims to evaluate the periodontal attachment and ankylosis status of teeth associated with cemento-osseous dysplasia (COD). Using resonance frequency analysis (RFA) and a bite force sensor, the stability of COD-associated teeth was measured and compared with contralateral healthy teeth. These non-invasive and objective methods are expected to reveal the impact of COD lesions on the surrounding dentoalveolar structures.
Cemento-osseous dysplasias represent the most common group of benign fibro-osseous lesions, frequently detected in the mandible and often asymptomatic. Although they generally do not require treatment, the remodeling of bone and cementum-like tissues around the tooth roots has clinical significance in terms of periodontal attachment and ankylosis. The present study aims to investigate the ankylosis status of teeth associated with COD lesions at different stages by using objective measurement tools.
In each patient, COD-associated teeth and contralateral healthy teeth were evaluated. Measurements were performed using resonance frequency analysis (RFA) with the Osstell™ device and additionally by a bite force sensor to assess functional stability. For RFA, SmartPeg magnetic attachments were fixed to the occlusal surface with composite resin, and three measurements were obtained in both mesio-distal and bucco-lingual directions. Mean ISQ values were then recorded. After measurements, SmartPeg was carefully removed without leaving residues, and patient comfort was evaluated using a six-point numeric rating scale.
The obtained RFA and bite force values will be statistically analyzed to compare COD-associated teeth with healthy controls. Furthermore, the study seeks to determine differences in ankylosis tendency across various COD stages and their potential impact on periodontal ligament integrity. This approach may provide valuable insights for understanding the clinical course of COD and for planning surgical interventions in symptomatic cases
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Teeth associated with cemento-osseous dysplasia were evaluated using Resonance Frequency Analysis (RFA) and a bite force sensor to assess ankylosis and stability.
Diagnostic Test: Resonance Frequency Analysis (RFA) · Diagnostic Test: Bite Force Sensor
Healthy contralateral teeth from the same patients, without cemento-osseous dysplasia, were evaluated using the same methods (RFA and bite force sensor) for comparison with COD-associated teeth.
Diagnostic Test: Resonance Frequency Analysis (RFA) · Diagnostic Test: Bite Force Sensor
Resonance frequency analysis performed with the Osstell™ device. SmartPeg was attached with composite resin to the occlusal surface of the tooth, and ISQ values were recorded in mesio-distal and bucco-lingual directions.
Assessment of maximum bite force using a bite force sensor. Measurements were performed on COD-associated teeth and contralateral healthy controls for comparison.
Implant Stability Quotient (ISQ) values by Resonance Frequency Analysis (RFA)
ISQ values obtained from COD-associated teeth and contralateral healthy teeth using the Osstell™ device. Measurements recorded in mesio-distal and bucco-lingual directions and averaged.
Time frame: At baseline (single measurement per tooth)
Maximum Bite Force
Bite force recorded with a bite force sensor to compare functional stability of COD-associated teeth and contralateral healthy teeth.
Time frame: At baseline (single measurement per tooth)
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Tooth Ankylosis
Eskisehir Osmangazi University