An observational study in Multiple Trauma/Injuries, sponsored by Melike Cengiz. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-09-22.
Sponsored by Melike Cengiz · Observational
Trauma is a public health concern that causes serious financial and medical burdens worldwide. According to the World Health Organization, 4.4 million people die from traumatic injuries each year which account for about 8% of global deaths. Traumatic injuries are among the most common causes of mortality particularly in young individuals. It also has a negative economic impact due to the loss of labor. Determining the factors associated with mortality in the ICU follow-up and treatment of these patients is very important for clarifying these uncertainties and improving ICU outcomes. The main objective of the study was to ascertain the ICU processes of multipletrauma patients and the factors that may have an effect on mortality.
All patients with traumatic injuries severe enough to warrant ICU admission formed the subjects of the study. The study included patients aged 18 years and over who were diagnosed with multiple trauma injuries and admitted to the ICU.The analysis included patients with a final outcome (survival or death) at our centre. Only patients who were admitted to the ICU for the first time were included. The following systems were used to assess the clinical and multiple trauma injury severity at the time of admission to the ICU: the Acute Physiology and Chronic Health Assessment II (APACHE II) score, the Simplified Acute Physiology Score II (SAPS II), the Sequential Organ Failure Assessment (SOFA) score, the Glasgow Coma Scale (GCS), the Injury Severity Score (ISS), the Revised Trauma Score (RTS) and the Trauma and Injury Severity Score (TRISS). All injury severity scores were calculated using clinical findings, imaging results and surgical findings. A comprehensive data set was collated at the time of admission to the intensive care unit, encompassing patient age, gender, comorbidities, and the Charlson Comorbidity Index (CCI). The injury mechanism, blood sugar, haemoglobin and lactate levels, Horowitz index, hypotension and hypothermia were also recorded.The patients were categorised into two groups: survival and mortality
139 studies on the registry are indexed under Multiple Trauma; 32 are open to participants now.
This study's enrollment of 269 is above the median of 200 across 84 observational studies indexed under Multiple Trauma.
Browse Multiple Trauma studies →Melike Cengiz is the lead sponsor of 7 studies on the registry; 1 is open to participants now.
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The sample included patients with multiple trauma injuries who were admitted in the ICU between 01 January 2021 and 01 November 2023.
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Exclusion Criteria:
consists of surviving patients
Other: Data of the patients were obtained from patient observation files and hospital information system database.
consists of deceased patients
Other: Data of the patients were obtained from patient observation files and hospital information system database.
Data of the patients were obtained from patient observation files and hospital information system database.
The primary outcome of the study is mortality
Time frame: 01 January 2021 and 01 November 2023
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Melike Cengiz