CClinicalTrials.gg
Active, not recruitingNCT07153510PIRUpdated Sep 4, 2025

"Comparative Effects of PIR and Static Stretching on Hamstring Flexibility" Post-Isometric Relaxation

An interventional study of Post-Isometric Relaxation and Active Static Stretching in Hamstring Tightness and Hamstring Flexibility, sponsored by University of Health Sciences Lahore. Active, not recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-09-04.

Sponsored by University of Health Sciences Lahore · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Sep 2025, 1 year 1 month ago, but the record still lists the study as active, not recruiting.
  • Registered 4 months after the study started (first participant enrolled Apr 2025, registered Aug 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
54
Allocation
Randomized
Ages
18 Years to 25 Years
Sex
All
01

Study summary

Hamstring tightness is a common problem among students and young adults, often leading to reduced flexibility, musculoskeletal discomfort, and risk of injury. Different stretching methods are used in physiotherapy practice to improve muscle length and flexibility. Post-Isometric Relaxation (PIR), a type of muscle energy technique, and Active Static Stretching (ASS) are two commonly applied methods, but evidence comparing their effectiveness in improving hamstring flexibility among Allied Health Sciences students remains limited.

This randomized controlled trial aims to compare the effects of PIR and Active Static Stretching on hamstring flexibility in healthy university students. Participants will be randomly assigned to either PIR or ASS groups and undergo stretching sessions for a specified duration. Hamstring flexibility will be measured using the Active Knee Extension test before and after the intervention. The findings will provide evidence to guide physiotherapy education and clinical practice on the most effective stretching technique for improving hamstring flexibility.

Read the detailed description

Hamstring muscle tightness is one of the most common musculoskeletal concerns in young adults, particularly in students of Allied Health Sciences who often spend prolonged hours in sitting postures during academic activities. Reduced hamstring flexibility is associated with altered posture, restricted range of motion, musculoskeletal discomfort, and a higher risk of lower limb injuries. Stretching interventions are widely used to address muscle tightness, with Post-Isometric Relaxation (PIR) and Active Static Stretching (ASS) being among the most frequently applied techniques in physiotherapy practice.

Post-Isometric Relaxation (PIR) is a form of muscle energy technique that utilizes a submaximal isometric contraction of the target muscle followed by a passive stretch, aiming to induce reflex relaxation and elongation of the muscle. Active Static Stretching (ASS) involves actively holding the muscle in a lengthened position for a fixed duration, relying on voluntary control and sustained tension to improve flexibility. While both techniques are clinically relevant, comparative evidence regarding their relative effectiveness in improving hamstring flexibility among young healthy populations, particularly Allied Health Sciences students, remains limited.

This randomized controlled trial is designed to compare the immediate and short-term effects of PIR and ASS on hamstring flexibility. A total of 54 students who meet the inclusion criteria will be randomly allocated to either the PIR group or the ASS group. Each group will undergo a structured stretching protocol for a specified period under supervision. Hamstring flexibility will be evaluated pre- and post-intervention using the Active Knee Extension (AKE) test, a valid and reliable measure of hamstring length.

The results of this study are expected to provide evidence on whether PIR or ASS is more effective for improving hamstring flexibility in this population. Findings will have important implications for physiotherapy education, clinical decision-making, and injury prevention strategies in young adults.

02

Conditions studied

  • Hamstring Tightness
  • Hamstring Flexibility

Keywords

  • Hamstring tightness,
  • Post Isometric Relaxation
  • Active Static Stretching
  • Students
  • Allied Health Sciences
03

In context

Lead sponsor

University of Health Sciences Lahore is the lead sponsor of 77 studies on the registry; 49 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 25 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Aged 18-25 years, Active Knee Extension (AKE) test angle > 20°, Willing to participate and provide informed consent

Exclusion criteria

Exclusion Criteria:

  • Any history of hamstring strain or lower limb injury in the past 6 months, Neurological or musculoskeletal disorders, Participation in other flexibility or stretching programs
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
54 participants (actual)

Study arms

  • Experimental
    Post-Isometric Relaxation

    Participants will undergo Post-Isometric Relaxation technique targeting the hamstring muscles. The technique involves an isometric contraction of the hamstring followed by a passive stretch. Participant will be in supine position; hip at 90° flexion, Isometric contraction of hamstrings for 7 seconds, Followed by 15 seconds of passive stretch, 10 repetitions, 3 times/week for 4 weeks

    Other: Post-Isometric Relaxation

  • Experimental
    Active Static Stretching

    Participants will perform Active Static Stretching exercises for the hamstrings, where the stretch is held actively without assistance.Seated long sitting position. Participant actively stretches hamstrings for 30 seconds. 10 repetitions, 3 times/week for 4 weeks

    Other: Active Static Stretching

Interventions

  • OtherPost-Isometric Relaxation

    Participants will undergo Post-Isometric Relaxation technique targeting the hamstring muscles. The technique involves an isometric contraction of the hamstring followed by a passive stretch. Participant will be in supine position; hip at 90° flexion, Isometric contraction of hamstrings for 7 seconds, Followed by 15 seconds of passive stretch, 10 repetitions, 3 times/week for 4 weeks

  • OtherActive Static Stretching

    Participants will perform Active Static Stretching exercises for the hamstrings, where the stretch is held actively without assistance.Seated long sitting position. Participant actively stretches hamstrings for 30 seconds. 10 repetitions, 3 times/week for 4 week

06

What researchers measure

Primary outcomes

  1. Hamstring flexibility

    Hamstring flexibility, assessed by the Active Knee Extension (AKE) test using a universal goniometer. Assessment Timeline: Baseline (Day 0) Post-intervention (End of Week 4)

    Time frame: 4 weeks

07

Study locations

1 site
  • University of Health Sciences
    Lahore, Punjab Province 54600, Pakistan
08

References and documents

Publications

  • Arif T, Mehmood W, Arif T. Comparison of post-isometric relaxation and active static stretching in improving hamstring flexibility among allied health sciences students: a randomized controlled trial. Sci Rep. 2026 May 6. doi: 10.1038/s41598-026-52130-5. Online ahead of print. PubMed 42092043 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07153510
Lead sponsor
University of Health Sciences Lahore
Responsible party
Tooba Arif (Dr. Tooba Arif, PT, University of Health Sciences Lahore) — Principal investigator
First posted
Sep 4, 2025
Start date
Apr 1, 2025
Primary completion
Sep 1, 2025 (estimated)
Completion
Sep 10, 2025 (estimated)
Last update
Sep 4, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

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