A Phase 1 interventional study of OTC Drug for Atopic Dermatitis in Cream form in Atopic Dermatitis (AD), sponsored by Good Molecules, LLC. Terminated at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-27.
Sponsored by Good Molecules, LLC · Phase 1, Interventional, and Treatment
This is a research study. The over-the-counter (OTC) drug for atopic dermatitis being tested is not approved as a treatment for the participants' atopic dermatitis condition. In participating in this study, the investigators will analyze the participants' skin microbiome, measure skin hydration and barrier function, and assess clinical improvements to help us understand the potential impact of the investigational OTC drug on atopic dermatitis and skin microbiome balance.
1,591 studies on the registry are indexed under Dermatitis, Atopic; 286 are open to participants now.
This study's enrollment of 3 is below the median of 82 across 1,246 interventional studies indexed under Dermatitis, Atopic.
Browse Dermatitis, Atopic studies →Good Molecules, LLC is the lead sponsor of 4 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
General:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Drug: OTC Drug for Atopic Dermatitis in Cream form
OTC Cosmetic Cream Formulation
Skin Microbiome Composition and Diversity using qPCR analysis
Time frame: 4 weeks
Trans-Epidermal Water Loss Measurement via Vapometer
Time frame: 4 weeks
Moisturizing effect by measurement of cutaneous hydration via MoistureMeterSC
Time frame: 4 weeks
Skin barrier lipid composition and integrity via lipidomic profiling analysis
Time frame: 4 weeks
Before and After Treated Arm Itching Assessment
In vivo clinical grading by a technician using a 11 point scale (0 = uncomfortable, irritated, and 10 = comfortable, soothed)
Time frame: 4 weeks
Before and After Treated Arm Redness Assessment
In vivo clinical grading by a technician using a 5 point scale (0 = absence of redness, and 4 = severe intensity)
Time frame: 4 weeks
Before and After Treated Arm Skin Dryness Assessment
In vivo clinical grading by a technician using a 11 point scale (0 = dry, cracked skin, and 10 = well-hydrated skin)
Time frame: 4 weeks
Monitoring of Atopic Dermatitis/Eczema Severity
Via the Patient Oriented Eczema Measure (POEM) tool
Time frame: 4 weeks
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
This study is terminated, as verified in May 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Good Molecules, LLC