An interventional study of Transcutaneous electrical acupoint stimulation and Sham transcutaneous Electrical Acupoint Stimulation in Postoperative Gastrointestinal Dysfunction (POGD), sponsored by The First Affiliated Hospital of Xiamen University. Recruiting at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-24.
Sponsored by The First Affiliated Hospital of Xiamen University · Not applicable, Interventional, and Treatment
The purpose of this clinical trial is to understand the effect of percutaneous acupoint electrical stimulation on postoperative gastrointestinal dysfunction. It will also investigate the safety of percutaneous acupoint electrical stimulation. The main questions that this trial aims to answer are:
Can percutaneous acupoint electrical stimulation alleviate postoperative gastrointestinal dysfunction? Through which mechanisms do they function?
Participants will:
Preoperatively, patients were either given or not given percutaneous acupoint electrical stimulation.
Record their symptoms and biological indicators within 5 days after the operation.
The First Affiliated Hospital of Xiamen University is the lead sponsor of 115 studies on the registry; 76 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Device: Sham transcutaneous Electrical Acupoint Stimulation
Device: Transcutaneous electrical acupoint stimulation
Before the operation, the patient received transcutaneous electrical acupoint stimulation (TEAS) at bilateral Zusanli (ST 36), Neiguan (PC 6), and Ciliao (BL 32) acupoints with sterilized electrode patches. The stimulation intensity and current intensity that gave the patient an effective pricking sensation ("deqi") were maintained for 30 minutes. The stimulation method in the post-anesthesia care unit (PACU) was consistent with that before the operation.
Before the operation, disinfection patches with electrodes were applied to Zusanli (ST 36), Neiguan (PC 6), and Ciliao (BL 32) acupointst, but no electrical stimulation was conducted. The stimulation method in the post-anesthesia care unit (PACU) was the same as that before the operation.
I-FEED(Intake, Feeling nauseated, Emesis, physical Exam, and Duration of symptoms)Score
The I-FEED score consists of five aspects: eating, nausea, vomiting, physical examination, and duration of symptoms. The lowest score is 0 and the highest is 14. The higher the score, the worse the result. The normal I-FEED score is 0-2 points. Postoperative gastrointestinal intolerance (POGI) is 3-5 points, and Postoperative gastrointestinal dysfunction (POGD) is ≥ 6 points.
Time frame: Three days after the operation
The time of the first postoperative defecation and flatus expulsion
Time frame: postoperative 3 days
The concentrations of motilin (MTL)
Time frame: postoperative 5 days
Platelet/lymphocyte ratio (PLR)
Time frame: postoperative 5 days
Visual analogue scale (VAS) Score
The VAS score refers to drawing a 10-cm scale on a piece of paper. One end of the scale is marked as 0, indicating no pain; the other end is marked as 10, indicating severe pain; the values in between represent different degrees of pain.
Time frame: postoperative 5 days
Quality-of-recovery 15 (Qor-15) Score
The QoR-15 includes 5 items related to physical comfort, 4 items regarding emotional state, 2 items concerning self-care ability, 2 items related to psychological support, and 2 items about pain. There are a total of 15 subjective parameters. Each item is scored on a scale of 0 to 10. The total score of QoR-15 ranges from 0 to 150. The higher the score, the better the condition.
Time frame: postoperative 5 days
miR-10b-5p
Time frame: postoperative 5 days
Interleukin-6 (IL-6)
Time frame: postoperative 5 days
Interleukin-10 (IL-10)
Time frame: postoperative 5 days
Acetylcholine (Ach)
Time frame: postoperative 5 days
Norepinephrine (NE)
Time frame: postoperative 5 days
Plan to share: No
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The First Affiliated Hospital of Xiamen University