An observational study in Brain Activity, sponsored by Centre Hospitalier St Anne. Not yet recruiting at 1 site in France. Open to participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2025-08-20.
Sponsored by Centre Hospitalier St Anne · Observational
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Linguistic irregularities in number naming systems, such as the inversion of number words, affect the processing of Arabic numerals. Recently, it has been claimed that there is even a syntactic representation of number words. participant investigate the neurofunctional correlates of the syntactic processing of number words by examining different levels of place-value processing in a study with two complementary successive phases (Group 1 and Group 2) in healthy adults. In the first phase with Group 1, participant evaluate the unit-decade compatibility effect (UDCE) in two-digit magnitude comparisons. In the second phase with Group 2, participant investigate the carry-over effect in two-digit addition problems.
Selection visit
Clinical examination:
Centre Hospitalier St Anne is the lead sponsor of 101 studies on the registry; 55 are open to participants now.
Counted across the registry records on this site, refreshed daily.
In the experimental phase, 42 adult volunteers (a total of 84), selected according to strict criteria, will undergo an MRI scan, each comprising: - anatomical acquisition, - functional acquisition of activation during a number processing task (Phase 1: two-digit number magnitude comparison; Phase 2: multi-digit mental arithmetic).
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraception
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
In each experimental phase (2 in total), 42 adult volunteers will be recruited (a total of 84 participants), selected based on the following criteria: * Aged 18-45 * Female or male * Right-handed * Signed informed consent * Normal medical, neurological, and neuroradiological examinations * Affiliated with a social security system * For women of childbearing age: under effective contraception; a urine pregnancy test will be administered * MRI examination compatible Participants will be recruited in the Paris region.
In each experimental phase (2 in total), 42 adult volunteers will be recruited (a total of 84 participants), selected based on the following criteria: * Aged 18-45 * Female or male * Right-handed * Signed informed consent * Normal medical, neurological, and neuroradiological examinations * Affiliated with a social security system * For women of childbearing age: under effective contraception; a urine pregnancy test will be administered * MRI examination compatible Participants will be recruited in the Paris region.
Neurofunctional variables (fMRI)
the comparison of pairs of incompatible numbers compared to pairs of compatible numbers during the comparison of numbers.
Time frame: Day 1
Structural variables (structural MRI)
the comparison of problems of addition with and without restraint during mental arithmetic.
Time frame: Day 1
Behavioral variables,
we compare performance to the post-imaging reading test
Time frame: Day 1
structural variables
recording of morphological and brain morphometric characteristics.
Time frame: Day 1
Handedness score
Measuring the lateralization of the hand will allow to recognize, based on the proposed activities, the dominant hand.
Time frame: Day 1
Demographics questionnaire
this questionnaire which will allow the collection of all the precise information about the participant
Time frame: Day 1
Start is estimated for Sep 2025; primary completion for Oct 2027, 25 months later.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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