CClinicalTrials.gg
CompletedNCT07127029Updated Aug 17, 2025

Effect of Petrolatum Coating on Fast-absorbing Gut Suture

An interventional study of Petrolatum coating of fast-absorbing gut suture in Suture, Suture Dermatologic and Mohs Micrographic Surgery, sponsored by San Antonio Uniformed Services Health Education Consortium. Completed. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-08-17.

Sponsored by San Antonio Uniformed Services Health Education Consortium · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 9 years 6 months after the study started (first participant enrolled Jan 2016, registered Aug 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
14
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Two gut sutures were placed into the skin of 14 healthy volunteers and randomized between coated and uncoated with petrolatum. Participants self-reported the time to resorption. The study concluded that there was no significant effect to the application of petrolatum, and reinforced that the gut sutures are a natural product with some inherent variability to their absorption.

02

Conditions studied

  • Suture
  • Suture Dermatologic
  • Mohs Micrographic Surgery
  • Suture Techniques
  • Dermatology
  • Closure Technique
  • Absorbable, Coated Sutures

Keywords

  • Petrolatum
  • Absorbable Suture
  • Gut Suture
  • Fast-absorbing Gut Suture
  • Wound Closure
  • Suture Coating
03

In context

Lead sponsor

San Antonio Uniformed Services Health Education Consortium is the lead sponsor of 7 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy volunteers within department of Dermatology
  • Able to receive care within the host facility (Dept of Defense)

Exclusion criteria

Exclusion Criteria:

  • current or planned pregnancy
  • Allergy to lidocaine
  • Infection on the shoulder site
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
Single (Participant)
Enrollment
14 participants (actual)

Study arms

  • Experimental
    6-0 Fast-Absorbing Gut Suture

    Two 6-0 fast-absorbing gut sutures were placed in the skin of deltoid, randomized to site A/B for the control (uncoated) and intervention (petrolatum coated) suture.

    Device: Petrolatum coating of fast-absorbing gut suture

Interventions

  • DevicePetrolatum coating of fast-absorbing gut suture

    6-0 fast absorbing gut suture was coated with sterile petrolatum and a single interrupted suture was placed into the skin of the deltoid

    Also known as: petrolatum coating

06

What researchers measure

Primary outcomes

  1. Length of time that suture remains intact in skin following petrolatum coating compared with standard fast-absorbing gut suture.

    Length of time in hours of suture remaining in skin prior to breakdown was recorded for both uncoated and coated suture.

    Time frame: Postprocedurally daily until suture is degraded (less than 2 weeks)

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Susong JR, Neiner JR. Effect of petrolatum coating on fast-absorbing gut suture. J Am Acad Dermatol. 2018 Nov;79(5):952-953. doi: 10.1016/j.jaad.2018.04.041. Epub 2018 Apr 30. No abstract available. PubMed 29723559 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 17, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07127029
Lead sponsor
San Antonio Uniformed Services Health Education Consortium
Responsible party
Jason Susong (Principal Investigator, San Antonio Uniformed Services Health Education Consortium) — Principal investigator
First posted
Aug 17, 2025
Start date
Jan 26, 2016
Primary completion
Oct 14, 2016
Completion
Oct 14, 2016
Last update
Aug 17, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion