An observational study in Lung Cancers and Bone Metastasis, sponsored by Guangdong Provincial People's Hospital. Completed at 1 site in China. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2025-08-03.
Sponsored by Guangdong Provincial People's Hospital · Observational
The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an established diagnosis of malignancy.
The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an established diagnosis of malignancy. By analyzing and contrasting these two groups, we seek to identify any distinctive characteristics, prognostic factors, and potential implications for early detection and treatment strategies in patients with malignant spinal metastases.
7,243 studies on the registry are indexed under Lung Neoplasms; 1,558 are open to participants now.
This study's enrollment of 139 is below the median of 189 across 1,512 observational studies indexed under Lung Neoplasms.
Browse Lung Neoplasms studies →Guangdong Provincial People's Hospital is the lead sponsor of 231 studies on the registry; 101 are open to participants now.
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The study population will consist of adult patients diagnosed with lung cancer who have developed spinal metastasis. Participants will be selected from individuals treated at Guangdong Provincial People's Hospital. Eligible patients must have a diagnosis of lung cancer with spinal metastasis confirmed by pathological examination or imaging studies, and must have undergone surgical intervention for spinal metastasis.
Exclusion Criteria:
It refers to patients who first present with symptoms such as pain or spinal cord compression caused by spinal metastasis, leading to the initial detection of bone metastasis, and are subsequently diagnosed with lung cancer.
It refers to patients with a history of treatment for primary lung cancer who subsequently developed spinal metastasis during the course of the disease.
Postoperative Overall Survival
Postoperative overall survival is defined as the time from the date of surgery for spinal metastasis to the date of death from any cause. Patients who are still alive at the last follow-up will be censored at that date. Survival status will be ascertained by clinical follow-up and/or review of medical records.
Time frame: From the date of surgery until death or last follow-up, up to 5 years
Plan to share: No — Individual participant data (IPD) will not be shared because of patient privacy concerns and local data protection regulations. Data may contain sensitive personal information that cannot be sufficiently anonymized to ensure participant confidentiality.
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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Guangdong Provincial People's Hospital