An observational study in Maxillary Deficiency, sponsored by University of Pavia. Enrolling by invitation at 1 site in Italy. Open to participants aged 6 Years to 14 Years. Per ClinicalTrials.gov, last updated 2025-11-18.
Sponsored by University of Pavia · Observational
Recruitment of patients treated using rapid maxillary expanders with dental anchorage, with pre-treatment panoramic X-rays and post-treatment models. In the initial phase of the study, the objective is to correlate the radiographic inclination of the upper permanent premolars in the pre-treatment orthopantomography to the expansion obtained at the end of therapy using a palatal expander with dental anchorage.
Maxillary transverse deficiency is a common malocclusion, frequently associated with unilateral or bilateral posterior crossbite, with a prevalence ranging from 8% to 22%. Since transverse development occurs earlier than vertical and sagittal development, inadequate transverse growth can also affect overall craniofacial development. This deficiency can impact aesthetics and functions such as creating excessive buccal corridor spaces, causing dental crowding, and reducing nasal cavity volume, which can lead to breathing difficulties. Thus, timely correction of maxillary transverse deficiency is crucial for harmonizing the relationship between the upper and lower jaws, as well as for enhancing aesthetics and functionality. Currently, rapid maxillary expansion (RME) is a widely accepted and established treatment for correcting maxillary constriction in patients during their peak growth period.
There is no protocol in the literature that investigates the need for transverse expansion of the upper jaw through the analysis of the inclination of the long axis of the upper premolars and canines. Therefore, the aim of this study is to investigate the predictability of the necessary expansion through the analysis of the inclination of the upper premolars and canines in orthopantomography.
In this retrospective study, patients who are scheduled for treatment using rapid palatal expanders with dental anchorage will be recruited. A requirement for recruitment will be the presence of pre-treatment orthopantomography.
The inclination of the tooth will be calculated between the long axis of the tooth and the middle line as previously described by Baccetti et all. In their works regarding impacted canines.
The achieved expansion will be evaluated based on the number of activations recorded in each individual patient's chart clinical records.
62 studies on the registry are indexed under Retrognathia; 15 are open to participants now.
This study's planned enrollment of 200 is above the median of 154 across 10 observational studies indexed under Retrognathia.
Browse Retrognathia studies →University of Pavia is the lead sponsor of 144 studies on the registry; 39 are open to participants now.
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Patients referring to the Unit of Orthodontics and Pediatric Dentistry for oral care
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Exclusion Criteria:
Patients treated with rapid palatal expansion. Patients must have a pre-treatment and post-treatment orthopantomography.
Other: Rapid palatal expansion
Patients undergone orthopedic treatment with rapid palatal expander
Number of required activation for maxillary expansion
Correlation between the number of activations of the rapid palatal expander and premolar inclination (angle between the long axis of the premolars with the occlusal plane)
Time frame: T0 (pre-treatment casts/x-rays) and T1 (post-treatment casts/x-rays)
Canine inclination
Angle between canines and the occlusal plane
Time frame: T0 (pre-treatment x-rays) and T1 (post-treatment x-rays)
Plan to share: No — Data will be available upon motivated request to the principal investigator.
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