An interventional study of Single-layer closure and Double-layer closure in Transvaginal Ultrasound, Caesarean Section and Uterine Scar, sponsored by Tanta University. Completed at 1 site in Egypt. Open to female participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2025-07-20.
Sponsored by Tanta University · Not applicable, Interventional, and Treatment
This study aimed to evaluate uterine scar thickness and integrity using transvaginal ultrasonography in women randomly assigned to single versus double-layer closure of the uterine incision, with a comparison between the two groups.
Cesarean section (CS) is one of the most commonly performed major abdominal operations in women in both high and low-income countries.
Single-layer closure using a running locking stitch is associated with decreased operative time and fewer additional haemostasis sutures. An extensive Canadian study found a fourfold increase in the risk of uterine rupture in a woman who had a single layer in their previous pregnancy.
Transvaginal ultrasound is a validated tool for evaluating uterine scar defects, commonly referred to as a niche. It is used to asses the uterine scar thickness in a women with previous cesarean delivery.
Tanta University is the lead sponsor of 963 studies on the registry; 304 are open to participants now.
Of its 16 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Patients who underwent single-layer closure of the transverse lower segment during cesarean section.
Procedure: Single-layer closure
Patients who underwent double-layer closure of the transverse lower segment during cesarean section.
Procedure: Double-layer closure
Patients who underwent single-layer closure of the transverse lower segment during cesarean section.
Patients who underwent double-layer closure of the transverse lower segment during cesarean section.
Uterine scar thickness
Uterine scar thickness was evaluated by transvaginal ultrasound six weeks, three months, and six months postoperative.
Time frame: 6 months postoperatively
Plan to share: Yes — The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Supporting information: Study protocol
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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