An observational study in Diabetes (DM) and Physical Activity, sponsored by Samsung Medical Center. Completed. Per ClinicalTrials.gov, last updated 2025-07-17.
Sponsored by Samsung Medical Center · Observational
Individuals with T2DM accompanied by abdominal obesity tend to experience worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators conducted a retrospective cohort study using data from the Korean National Health Insurance Service (K-NHIS) database to evaluate the impact of regular physical activity.
It is well established that patients with T2DM and abdominal obesity have worse clinical outcomes. This holds true even among individuals with a normal body weight but central (abdominal) obesity. In this study, the investigators aimed to determine whether engaging in regular physical activity (defined as vigorous exercise at least three times per week) is associated with improved clinical outcomes in normal-weight individuals with abdominal obesity. Specifically, we compared the incidence of MACCE between normal-weight patients with type 2 diabetes who had abdominal obesity and those who did not.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's enrollment of 249,247 is above the median of 233 across 2,220 observational studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →Samsung Medical Center is the lead sponsor of 980 studies on the registry; 146 are open to participants now.
Of its 7 completed or terminated interventional studies of FDA-regulated products, 1 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients who were newly diagnosed with T2DM and had a normal body weight at the time of diagnosis.
- Patients who were newly diagnosed with T2DM and had a normal body weight at the time of diagnosis.
Exclusion Criteria:
Individuals were classified as having abdominal obesity.
Behavioral: Regular physical activity · Behavioral: No regular physical activity
Individuals were classified as not having abdominal obesity.
Moderate-to-vigorous physical activity at least three times per week.
The group that did not engage in physical activity according to the guidelines
Major adverse cardiac and cerevrovascular events (MACCE)
Composite of all-cause death, myocardial infarction, ischemic stroke, heart failure
Time frame: 10 years after diagnosed T2DM
All cause death
Death from all cause
Time frame: 10 years after diagnosed T2DM
myocardial infarction
MI with hospitalization
Time frame: 10 years after diagnosed T2DM
Ischemic stroke
Ischemic stroke after diagnosed T2DM
Time frame: 10 years after diagnosed T2DM
Heart failure
HF with hospitalization
Time frame: 10 years after diagnosed T2DM
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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Samsung Medical Center