ClinicalTrials.gg
Active, not recruitingNCT07068360Updated Jul 16, 2025

Development and Validation of MPF to Prevent and Mitigate Postural Hyperkyphosis in Postmenopausal Women

An interventional study of Strength Training +Postural Correction Exercises + Balance Training +Flexibility Exercises and Standard Intervention (Control Group) in Hyperkyphosis, sponsored by Superior University. Active, not recruiting at 1 site in Pakistan. Open to female participants aged 35 Years to 70 Years. Per ClinicalTrials.gov, last updated 2025-07-16.

Sponsored by Superior University · Not applicable, Interventional, and Health services research

From the registry’s dates

  • Primary completion was expected by Dec 2025, 11 months ago, but the record still lists the study as active, not recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
72
Allocation
Randomized
Ages
35 Years to 70 Years
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 10 studies in Kyphosis with a site in Pakistan — 3 open to participants now, 5 under way, none of them phase 3. Kyphosis · Pakistan.

Enrollment
2nd of 10
72 · median 36
Started
2025
with 2 others
No phase
10 of 10
3 open now
Registered
9th of 10
by date
Lead sponsor
1 of 10
Superior University

Among the 10 studies in Kyphosis with a site in Pakistan, this one is the 2nd largest by enrollment, is one of 3 that started in 2025, is one of 10 with no phase, and was the 9th registered.

Kyphosis

132 studies on the registry are indexed under Kyphosis; 31 are open to participants now.

Browse Kyphosis studies →

Open to participants now

3 of the 10 studies in Kyphosis with a site in Pakistan are open now. Recruiting first, the newest first:

All 3 open studies →

A study can be open while its sites in Pakistan have not opened yet or have stopped. Only those recruiting at a site in Pakistan →

Who these studies take

Of the 20 Kyphosis studies recruiting now, 7 (35%) set no upper age limit and 12 (60%) stop at 75 or younger; 7 take children under 18; 1 take healthy volunteers.

This study: 35 Years to 70 Years · female · no healthy volunteers.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

Was this useful?
Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 10 studies in Kyphosis with a site in Pakistan, or all of them as a file.
02

Study summary

Postural hyperkyphosis is common in postmenopausal women and leads to spinal dysfunction, pain, impaired balance, and increased fall risk. This study aims to develop and validate a multimodal physiotherapy framework to prevent and manage hyperkyphosis in this population. A randomized controlled trial will be conducted at Allied Hospital with 72 postmenopausal women aged 40-75 years, divided into intervention (multimodal physiotherapy with conventional care) and control (conventional care only) groups.

Read the detailed description

The intervention includes strength, flexibility, postural correction, and balance training. The primary outcome is the change in Cobb's angle measured via radiographs; secondary outcomes include functional mobility and balance assessments using the Timed Up and Go Test, Berg Balance Scale, and Functional Reach Test. Data will be analyzed using SPSS v26. The study is expected to show significant improvements in spinal alignment, strength, balance, and reduced fall risk. The framework may offer a cost-effective, evidence-based approach for clinical and community rehabilitation

03

Conditions studied

  • Hyperkyphosis

Browse trials for

04

Who can participate

Ages eligible
35 Years to 70 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • women aged 50-70 years.
  • Kyphotic angle ≥40°, as measured by a flexicurve ruler or radiographic assessment.
  • Postmenopausal for at least one year.
  • Able to engage in rehabilitation exercises and follow instructions for physical activity..
  • Living independently and capable of attending regular physiotherapy sessions.

Exclusion criteria

Exclusion Criteria:

  • Uncontrolled comorbidities such as cardiovascular disease, neurological disorders stroke or Parkinson's), or severe musculoskeletal conditions (e.g., advanced arthritis )
  • History of spinal surgery within the last 6 months or spinal surgical implants. Severe osteoporosis (T-score \< -2.5) and a history of multiple fractures.
  • Pregnant or breastfeeding women. Cognitive impairments or mental health disorders that hinder adherence to the intervention.
  • Inability to perform the exercises due to pain or disability.
  • Participation in other rehabilitation or physiotherapy interventions for postural hyperkhyposis
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Postmenopausal

Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).

05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
72 participants (actual)

Study arms

  • Experimental
    Strength Training +Postural Correction Exercises + Balance Training +Flexibility Exercises

    Combination Product: Strength Training +Postural Correction Exercises + Balance Training +Flexibility Exercises

  • Active comparator
    Standard Intervention (Control Group)

    Diagnostic Test: Standard Intervention (Control Group)

Interventions

  • Combination productStrength Training +Postural Correction Exercises + Balance Training +Flexibility Exercises

    Interventions details (Group A) Strength Training Postural Correction Exercises Balance Training Exercises Flexibility Exercises:

  • Diagnostic testStandard Intervention (Control Group)

    The control group will receive standard physiotherapy for postural hyperkyphosis. The standard intervention will consist of: Postural education: Educating participants on proper posture, body mechanics, and ergonomics in daily activities. Basic stretching exercises targeting the thoracic spine and back muscles. Recommendations for low-impact aerobics activities (e.g., walking or cycling) to promote overall healthThe standard intervention will be delivered over the same 12-week period, with two sessions per week. This group will not receive the integrated multimodal framework with strength training, postural correction, balance training, and flexibility exercises that the experimental group receives. Duration and Frequency

06

What researchers measure

Primary outcomes

  1. Cobb's Angle

    Cobb's Angle is a radiographic measurement used to assess spinal curvature in conditions like hyperkyphosis and scoliosis. It is calculated by identifying the most tilted vertebrae at the top and bottom of the curve on an X-ray. Straight lines are drawn along their endplates, and perpendiculars from these lines intersect to form the Cobb's Angle. A normal thoracic kyphosis ranges from 20° to 40°, while angles exceeding 40° in adults or 50° in postmenopausal women indicate hyperkyphosis. Severe cases (\>60°) may require medical intervention. Regular follow-ups help monitor treatment effectiveness in reducing spinal curvature.

    Time frame: 18 Months

  2. Timed Up and Go (TUG) Test

    The TUG test assesses mobility, balance, and fall risk in older adults. The patient starts seated in a chair, stands up, walks 3 meters (10 feet), turns around, walks back, and sits down. The time taken to complete the task is recorded in seconds. A score of \<10 seconds indicates normal mobility, 10-20 seconds suggests mild mobility impairment, and \>30 seconds signifies a high fall risk and functional dependence. It is a simple, reliable tool commonly used in rehabilitation settings.

    Time frame: 18 Months

  3. Berg Balance Scale (BBS)

    The BBS is a 14-item test used to assess balance and fall risk in older adults and neurological patients. Each task, such as standing on one foot or reaching forward, is scored from 0 to 4, with a total score of 56. A score of 41-56 indicates low fall risk, 21-40 suggests moderate risk, and ≤20 signifies a high risk of falls. The test is widely used due to its strong reliability and validity in clinical practice.

    Time frame: 18 Months

07

Study locations

1 site
  • Faisalabad Medical University (Allied Hospital Faisalabad)
    Faisalābad, Punjab Province, Pakistan
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Apr 2025 (actual). Primary completion is estimated for Dec 2025, 7 months after the start.

Of 56 non-industry interventional studies with no phase under Kyphosis, half reached primary completion within 9 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 30. This study's planned 7 months is below that.

Counting every sponsor, half of 58 studies reached it within 9 months; a quarter within 4 and three quarters within 30.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 7, 2025
First posted
Jul 16, 2025
StartActual
Apr 17, 2025
Primary completionEst.
Dec 1, 2025
CompletionEst.
Jun 1, 2026
Last update
Jul 16, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 16, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07068360
Responsible party
Muhammad Naveed Babur (Principal Investigator, Superior University) — Principal investigator
First posted
Jul 16, 2025
Start date
Apr 17, 2025
Primary completion
Dec 1, 2025 (estimated)
Completion
Jun 1, 2026 (estimated)
Last update
Jul 16, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion