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CompletedNCT07066618Updated Jul 15, 2025

Effects of Meal Energy Density on Body Measures and Metabolism in Women

An interventional study of Breakfast-Loaded Hypocaloric Diet and Dinner-Loaded Hypocaloric Diet in Obesity, Overweight and Appetite Regulation, sponsored by Melike Nur Eroğlu. Completed at 1 site in Turkey (Türkiye). Open to female participants aged 20 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-15.

Sponsored by Melike Nur Eroğlu · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 7 months after the study started (first participant enrolled Nov 2023, registered Jun 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
28
Allocation
Randomized
Ages
20 Years to 45 Years
Sex
Female
01

Study summary

This study investigates whether the timing of energy intake during the day-specifically consuming more calories at breakfast or at dinner-affects body measurements, blood sugar levels, cholesterol, and feelings of hunger in women who are overweight or obese.

A total of 28 women participated in the study and were randomly assigned to one of two diet plans: one group consumed half of their daily calories at breakfast, while the other consumed them at dinner. Both groups followed a calorie-restricted diet for six weeks.

The goal of this research is to understand whether eating more in the morning rather than in the evening leads to better outcomes for weight control and metabolic health. Findings from this study may help health professionals make more effective meal timing recommendations for weight loss and improving blood sugar regulation.

02

Conditions studied

  • Obesity
  • Overweight
  • Appetite Regulation
  • Meal Timing
  • Circadian Rhythm
  • Metabolic Health

Keywords

  • circadian rhythm
  • appetite
  • Meal Timing
  • obesity
  • Glucose Metabolism
03

In context

Obesity

6,296 studies on the registry are indexed under Obesity; 1,692 are open to participants now.

This study's enrollment of 28 is below the median of 78 across 4,878 interventional studies indexed under Obesity.

Browse Obesity studies →

Lead sponsor

Melike Nur Eroğlu is the lead sponsor of 3 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 45 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Women aged 20-45
  • BMI ≥25 kg/m²
  • Regular menstrual cycle
  • No chronic disease or medication use
  • PSQI ≤5 (Good sleep quality)

Exclusion criteria

Exclusion Criteria:

  • Pregnancy or lactation
  • Gastrointestinal or metabolic disorders
  • Shift workers, sleep disorders
  • Medication affecting metabolism
  • Weight change >4.5 kg in last 6 months
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
28 participants (actual)

Study arms

  • Experimental
    Breakfast Group (BG)

    Behavioral: Breakfast-Loaded Hypocaloric Diet

  • Experimental
    Dinner Group (DG)

    Behavioral: Dinner-Loaded Hypocaloric Diet

Interventions

  • BehavioralBreakfast-Loaded Hypocaloric Diet

    Participants in this group consumed a hypocaloric diet in which 50% of daily energy intake was provided at breakfast, 35% at lunch, and 15% at dinner. Meal times were standardized as follows: breakfast (7:00-9:00), lunch (12:00-14:00), and dinner (18:00-20:00). The diet was individually tailored and provided 20% fewer calories than the participants' total energy expenditure. Macronutrient distribution followed recommended guidelines: 45-60% carbohydrates, 10-20% protein, and 20-35% fat.

  • BehavioralDinner-Loaded Hypocaloric Diet

    Participants in this group consumed a hypocaloric diet in which 15% of daily energy intake was provided at breakfast, 35% at lunch, and 50% at dinner. Meal times were standardized as follows: breakfast (7:00-9:00), lunch (12:00-14:00), and dinner (18:00-20:00). The diet was individually tailored and provided 20% fewer calories than the participants' total energy expenditure. Macronutrient distribution followed recommended guidelines: 45-60% carbohydrates, 10-20% protein, and 20-35% fat.

06

What researchers measure

Primary outcomes

  1. Change in fasting blood glucose

    Time frame: Baseline to Week 6

Secondary outcomes

  1. Change in hip circumference

    Time frame: Baseline to Week 6

  2. Change in HDL cholesterol

    Time frame: Baseline to Week 6

  3. Change in HbA1c

    Time frame: Baseline to Week 6

07

Study locations

1 site
  • Sakarya University of Applied Sciences, Faculty of Sport Sciences, Exercise and Sports Sciences Education, Application and Research Centre
    Sakarya, Turkey (Türkiye)
08

References and documents

Study documents

  • Informed consent form · Nov 1, 2023

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: Yes

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 15, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07066618
Lead sponsor
Melike Nur Eroğlu
Responsible party
Melike Nur Eroğlu (Lecturer, Sakarya Applied Sciences University) — Sponsor-investigator
First posted
Jul 15, 2025
Start date
Nov 15, 2023
Primary completion
Mar 20, 2024
Completion
Mar 25, 2024
Last update
Jul 15, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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