An interventional study of Mupirocin (drug) and Hydrocolloid Dressing (DuoDERM CGF) in Biopsy Wound, sponsored by University of Santo Tomas Hospital, Philippines. Completed at 1 site in Philippines. Open to participants aged 18 Years to 64 Years. Per ClinicalTrials.gov, last updated 2025-08-24.
Sponsored by University of Santo Tomas Hospital, Philippines · Not applicable, Interventional, and Treatment
The main objective of this study is to determine the efficacy of using hydrocolloid dressing on wound healing of post-punch biopsy wounds vs topical antibiotic. Specifically, it aims to measure the following parameters: the presence or absence of infection, the clinical estimate of reepithelialization, the clinical estimate of wound closure, scar formation, pigmentation of scar, and the cosmetic appearance of the wound.
The study is a double-blind randomized controlled trial which will be conducted at the Dermatology outpatient department and the private clinics of dermatology consultants of the University of Santo Tomas Hospital. Patients who will be included are those who are 18 to 64 years of age with clean cutaneous lesions. Excluded from this study are those who have infected wounds, those who have conditions with poor tendency to heal including diabetes mellitus, peripheral vascular disease, history of keloid formation, those currently receiving anticoagulation therapy or systemic corticosteroids, and those known to have hypersensitivity to topical antibiotics.
The primary outcome measure is the proportion of patients who achieved better overall healing when treated with hydrocolloid dressing.
University of Santo Tomas Hospital, Philippines is the lead sponsor of 4 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Skin punch biopsy wound treated with hydrocolloid dressing.
Drug: Hydrocolloid Dressing (DuoDERM CGF)
Skin punch biopsy wound treated with topical antibiotic.
Drug: Mupirocin (drug)
Wounds were dressed with gauze impregnated with mupirocin ointment covered by a transparent dressing (Tegaderm)
Also known as: Mupirocin ointment, Antimicrobial, Topical antibacterial
Wounds were dressed with a 1-inch size Duoderm Control Gel Formula hydrocolloid dressing
Also known as: hydrocolloid
Absence or Presence of Infection
Absent - millimeters of surrounding erythema or equivocal findings Present - as inferred by indurated erythema or purulent discharge
Time frame: 5 days after punch biopsy.
Clinical Estimate of Reepithelialization
Rated on a scale of: * 0% to 25% * 26% to 50% * 51% to 75% * 76% to 100%
Time frame: 5 days after punch biopsy
Clinical Estimate of Wound Closure
Rated on a scale of: * 0% to 25% * 26% to 50% * 51% to 75% * 76% to 100%
Time frame: 5 days after punch biopsy
Scar Formation
Select one of the following for the assessment: * Unhealed * Depressed or Atrophied * Normal fine-line scar * Hypertrophied scar or Keloid
Time frame: 5 days after punch biopsy
Scar Pigmentation
Select one of the following for the assessment: * Indeterminate or Unhealed * Normal * Hyperpigmented * Hypopigmented
Time frame: 5 days after punch biopsy
Cosmetic Appearance
Select one of the following for the assessment: * Indeterminate or Unhealed * Poor * Fair * Good * Excellent
Time frame: 5 days after punch biopsy
Documents are hosted by the registry — open the source record to download them.
Plan to share: No — Sharing of the individual participant data was not part of the patient informed consent form.
This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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University of Santo Tomas Hospital, Philippines