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RecruitingNCT07061119ASDUpdated Jul 11, 2025

Effect of Cawthorne Cooksey Exercises on Balance in Autistic Children With Vestibular Hypofunction.

An interventional study of Conventional treatment and cawthorne cooksey exercises in Autism Spectrum Disorder and Vestibular Hypofunction, sponsored by Riphah International University. Recruiting at 1 site in Pakistan. Open to participants aged 7 Years to 15 Years. Per ClinicalTrials.gov, last updated 2025-07-11.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jul 2025, 1 year 2 months ago, but the record still lists the study as recruiting.
  • Registered 5 months after the study started (first participant enrolled Jan 2025, registered Jul 2025).
  • Started Jan 2025; still recruiting 1 year 8 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
44
Allocation
Randomized
Ages
7 Years to 15 Years
Sex
All
01

Study summary

The objective of the study is to determine the effects of cawthorne cooksey exercises on balance in autistic children with vestibular hypofunction. The study will be randomized control trial including 2 experimental groups with estimated 22 participants in each group.

Read the detailed description

The complex neurodevelopmental disorder known as autism spectrum disorder (ASD) affects people in a variety of ways, affecting their ability for social interaction, communication, and repetitive behavior. Typically, ASD is recognized and diagnosed in the early childhood years, although its impact can extend throughout a person's life. Autism Spectrum Disorder (ASD) is a type of condition that affects how a child's brain develops. It appears that they have a somewhat different brain than others, which may have an impact on their behavior, social interactions, and communication. It can involve repetitive actions and a strong focus on specific interests. Symptoms of autism differ from person to person depending on age and ability that's why it is called spectrum disorder. Children with autism spectrum disorder appear to exhibit altered postural control when facing challenging situations. Postural control predominantly relies on the automatic system, necessitates focused attention during various straightforward or intricate tasks, and facilitates the regulation of postural control.

Vestibular functioning refers to operation and effectiveness of vestibular system, which is normally concerned with spatial orientation, movement, and balance. The system is located in the inner ear and comprises of semicircular canals (fluid-filled canals) and sensory receptors. Vestibular dysfunction is another common manifestation is autistic patients. It refers to impaired ability to sense and process sensory information associated with balance, movement, and spatial orientation. The manifestations of vestibular dysfunction include apprehensive behaviors when feet do not touch the ground, avoidance of jumping/climbing, and escaping activities like playing with playground equipment. The children usually exhibit toe walking and take more risks while playing. Interventions to improve balance due to vestibular dysfunction include trampoline Jumping, Gym ball exercises, balance board exercises. Balance issues play a huge role in life of an individual with autism. There is indeed a huge gap and lack of literature on how or if exercise protocols from physical therapy can influence balance in individuals with autism. Although, Previous studies have recommended that Balance issues and autism are directly related and that vestibular dysfunction plays a huge role in maintenance of posture. The aim of the study is to investigate the effects of Cawthorne Cooksey exercises on balance. This study will also influence how a physical therapist can improve quality of life of an individual with autism by improving their balance

02

Conditions studied

  • Autism Spectrum Disorder
  • Vestibular Hypofunction

Keywords

  • Autism, vestibular rehab in children, Autism and balance
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In context

Autism Spectrum Disorder

1,727 studies on the registry are indexed under Autism Spectrum Disorder; 504 are open to participants now.

This study's planned enrollment of 44 is below the median of 52 across 1,371 interventional studies indexed under Autism Spectrum Disorder.

Browse Autism Spectrum Disorder studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
7 Years to 15 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Both genders
  • Peripheral Vestibular hypofunction.
  • Age:7-15years
  • Children with mild to moderate autism.
  • Children who understand and communicate

Exclusion criteria

Exclusion Criteria:

  • Central Vestibular.
  • Acute Infection of inner ear
  • Auditory issues.
  • Patients unable to follow exercise plan
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
44 participants (estimated)

Study arms

  • Active comparator
    Conventional treatment

    Conventional treatment include: Trampoline jumping Gym ball exercise:5reps'Sensory diet: Joint compressions Deeppressure Balance board exercises

    Other: Conventional treatment

  • Experimental
    Participant Group

    Cawthorne cooksey exercises

    Other: cawthorne cooksey exercises

Interventions

  • OtherConventional treatment

    Trampolinejumping:5times. Gym ball exercise:5reps'Sensory diet:- Joint compressions: 1 set x 10reps on limbs, neck, and head region. Deeppressure:1 setx10reps. Balance board exercises.

  • Othercawthorne cooksey exercises

    Cawthorne Cooksey exercises * Start with low to moderate intensity. * Gradually increase range, speed, and Complexity over time * Trampoline jumping- Gym ball exercise- Sensory diet * Cawthorne Cooksey exer cise Training Phase1-In bed exerercises:- Eye movements: 1)Up and down 2)Side to side 3)Moving finger away from face * Phase2-Sitting: Eye movements as above. Head movements at firsts low, then quick later with eyes closed * bending forward and backward * turning from side to side. --Shoulder shrugging and circling * Bending forward and picking up objects from the ground * Phase 3 - Standing: * Eye, Head, Shoulder movements * Throwing ball from hand to hand, hand under knee * Switch to sitting to standing and turning around in between. * Phase 4 - Walk: with eyes closed and open: * Across room * Slope and Stairs

06

What researchers measure

Primary outcomes

  1. Pediatric Balance Scale (PBS)

    Adapted from the Berg Balance Scale for pediatric use.Assesses flexibility in changing postures and overall postures. - Comprises 14 different balance- related tasks, scored from 0 to 4. Used to assess functional balance skills and motor disorders in school-aged children.

    Time frame: 6 Weeks

  2. CTSIB-M

    This test is aimed to asses' sensory input when one or more sensory system is compromised. It Assess balance (either vestibular or non- vestibular). It consists of 4 different conditions; 4 conditions e.g. eye open/ eye close and firm surface. Eyes open/ eye close foam surface. each consist of 3 trials. Total time 30 sec for each trial and total score is 120. Excellent reliability and validity.

    Time frame: 6 Weeks

07

Study locations

1 of 1 sites recruiting
  • Islamabad, Pakistan
    Islamabad, Fedral 04403, Pakistan
    Recruiting
08

References and documents

Publications

  • Lord C, Brugha TS, Charman T, Cusack J, Dumas G, Frazier T, Jones EJH, Jones RM, Pickles A, State MW, Taylor JL, Veenstra-VanderWeele J. Autism spectrum disorder. Nat Rev Dis Primers. 2020 Jan 16;6(1):5. doi: 10.1038/s41572-019-0138-4. PubMed 31949163 ↗
  • Mughal S, Faizy RM, Saadabadi A. Autism spectrum disorder. 2018
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 11, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07061119
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Jul 11, 2025
Start date
Jan 31, 2025
Primary completion
Jul 31, 2025 (estimated)
Completion
Jul 31, 2025 (estimated)
Last update
Jul 11, 2025

Study contacts

Nadia Azhar, MS-NMPT
Contact
Nadia.azhar@riphah.edu.pk
00923335281431
Nadia Azhar, MS
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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