An interventional study of cervical collar or cervical-thoracic orthosis. and chin-to-chest (Grillo) suturing in Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection, sponsored by Sohag University. Recruiting at 1 site in Egypt. Open to participants aged 6 Months to 80 Years. Per ClinicalTrials.gov, last updated 2025-07-10.
Sponsored by Sohag University · Not applicable, Interventional, and Treatment
Tracheal surgery represents a relatively recent advancement in the field of thoracic surgery. The trachea has unique anatomical and physiological challenges that historically rendered surgical manipulation both risky and limited. Early interventions involving the trachea were primarily restricted to emergency tracheostomy procedures, typically performed as life-saving measures during acute airway obstruction (1). Attempts at tracheal reconstruction were largely unsuccessful due to the absence of suitable anesthesia, inadequate surgical tools, and the prevailing belief that tracheal cartilage lacked sufficient regenerative. As a result, tracheal resection and reconstruction were long considered unfeasible (2).
The modern era of tracheal surgery began to take shape in the mid-20th century. While early attempts at tracheal resection were performed with limited success, it was the pioneering work of Dr. Hermes C. Grillo in the 1960s that truly transformed the field. Through systematic study of tracheal anatomy, vascular supply, and biomechanics, Dr. Grillo developed standardized and safe techniques for segmental tracheal resection followed by primary end-to-end anastomosis. His work demonstrated that segmental resection of the trachea followed by primary end-to-end anastomosis was feasible and safe (3)(4).
Sohag University is the lead sponsor of 1,183 studies on the registry; 612 are open to participants now.
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Exclusion Criteria:
Patients in this group will have postoperative cervical spine flexion maintained using non-invasive techniques, such as a cervical collar or cervical-thoracic orthosis.
Procedure: cervical collar or cervical-thoracic orthosis.
Patients in this group will have cervical spine flexion maintained using traditional chin-to-chest (Grillo) suturing
Device: chin-to-chest (Grillo) suturing
postoperative cervical spine flexion maintained using non-invasive techniques, such as a cervical collar or cervical-thoracic orthosis.
cervical spine flexion maintained using traditional chin-to-chest (Grillo) suturing
cervical spine flexion
Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection
Time frame: 2 years
Plan to share: Undecided
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