CClinicalTrials.gg
CompletedNCT07054658Updated Jul 22, 2025

Evaluation of Allogenic Bone Ring Graft With Simultaneous Implant Placement for Vertical Ridge Augmentation

An interventional study of Allogenic Bone Ring Graft With Simultaneous Implant Placement in Posterior Mandible With Deficient Ridge Height, sponsored by Tanta University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-07-22.

Sponsored by Tanta University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 1 month after the study started (first participant enrolled May 2024, registered Jun 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
10
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

This clinical trial aimed to evaluate the effectiveness of vertical ridge augmentation using customized allogenic bone ring grafts with simultaneous dental implant placement in the posterior mandible. The procedure is designed to address vertical bone deficiencies without the need for autogenous bone harvesting, thereby reducing patient morbidity and surgical complexity. The study assessed clinical outcomes including bone gain, implant stability, and over a 6-month period and inflammation, infection, pain and neurosensory changes where assessed for 4 weeks.

Read the detailed description

This study investigated the clinical outcomes of vertical ridge augmentation using allogenic bone rings in combination with simultaneous implant placement for the treatment of posterior mandibular bone defects. Traditional ridge augmentation techniques often require two-stage surgeries and autogenous bone harvesting, which may increase patient morbidity and prolong healing. In contrast, the allogenic bone ring technique provides a one-stage approach by allowing vertical augmentation and implant placement to be performed simultaneously.

The study was designed as a prospective, single-arm clinical trial. Eligible patients aged 18 years or older, presenting with vertical bone deficiencies in the posterior mandible, were recruited from the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University. The primary outcome was vertical bone gain measured radiographically at 6 months postoperatively. Secondary outcomes included implant stability (measured by IST), soft tissue healing, and postoperative complications. Patients were followed clinically and radiographically to evaluate the success of the grafting procedure and implant integration.

02

Conditions studied

  • Posterior Mandible With Deficient Ridge Height

Keywords

  • vertical ridge augmentation
  • bone ring technique
03

In context

Lead sponsor

Tanta University is the lead sponsor of 963 studies on the registry; 304 are open to participants now.

Of its 16 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Participants with vertical alveolar ridge atrophy in the posterior mandible who are motivated, cooperative, and have good oral hygiene.
  • Minimum of 7 mm remaining bone height from the crest of the alveolar ridge to the inferior alveolar canal.
  • Patients with adequate remaining interarch space

Exclusion criteria

Exclusion Criteria:

  • Prior local radiation therapy.
  • Soft and hard tissue pathology at the operation site.
  • Systemic diseases that might affect bone healing and osseointegration (e.g., uncontrolled diabetes)..
  • smokers who consume 20 or more cigarettes per day.
  • patients on anti-resorptive drugs (eg: bisphosphonates and denosumab).
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
10 participants (actual)

Study arms

  • Experimental
    Allogenic Bone Ring With Simultaneous Implant Placemen

    Patients received vertical ridge augmentation using a customized allogenic bone ring graft with simultaneous dental implant placement in the posterior mandible

    Procedure: Allogenic Bone Ring Graft With Simultaneous Implant Placement

Interventions

  • ProcedureAllogenic Bone Ring Graft With Simultaneous Implant Placement

    A surgical procedure involving vertical ridge augmentation using an allogenic bone ring combined with simultaneous dental implant placement in the posterior mandible. The technique allows one-stage treatment of vertical bone defects without the need for autogenous bone harvesting.

06

What researchers measure

Primary outcomes

  1. Vertical Bone Gain in mm

    The vertical bone gain was measured radiographically using CBCT imaging to evaluate the effectiveness of the allogenic bone ring graft in augmenting vertical bone height in the posterior mandible

    Time frame: 6 months postoperatively

07

Study locations

1 site
  • Faculty of Dentistry, Tanta University
    Tanta, Gharbia Governorate 31527, Egypt
08

References and documents

Publications

  • Hussein IT, Beder RR, Saad KA, Breshah MN. Evaluation of allogenic bone ring graft with simultaneous implant placement for vertical ridge augmentation. Oral Maxillofac Surg. 2025 Dec 1;30(1):4. doi: 10.1007/s10006-025-01487-4. PubMed 41320709 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 22, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07054658
Lead sponsor
Tanta University
Responsible party
Ibrahim Taha Hussein (Principal Investigator, Tanta University) — Principal investigator
First posted
Jul 8, 2025
Start date
May 23, 2024
Primary completion
Jan 31, 2025
Completion
Feb 27, 2025
Last update
Jul 22, 2025

Study contacts

Ibrahim T Hussein
principal investigator · Faculty of Dentistry, Tanta University, Egypt
Rafic R Beder
principal investigator · Faculty of Dentistry, Tanta University, Egypt
Khaled A Saad
principal investigator · Faculty of Dentistry, Tanta University, Egypt
Maram N Breshah
principal investigator · Faculty of Dentistry, Tanta University, Egypt

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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