An observational study in Comprehensive Geriatric Assessment, Chronic Disease Management and Older Adults (65 Years and Older), sponsored by Henan Provincial People's Hospital. Not yet recruiting. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-24.
Sponsored by Henan Provincial People's Hospital · Observational
With the continuous development of China's economy and the improvement of medical standards, the life expectancy of the Chinese population has significantly increased. Against the backdrop of accelerating aging in China, the incidence of age-related chronic non-communicable diseases (NCDs), such as cardiovascular and cerebrovascular diseases and chronic respiratory diseases, has risen remarkably. These diseases are characterized by multiple comorbidities, high disability rates, and high mortality rates, severely compromising the quality of life of older adults, exacerbating family burdens, and straining healthcare systems. This constitutes one of the major challenges faced by aging societies. Therefore, early detection and intervention of chronic diseases in older adults are critical measures to address population aging.
Comprehensive geriatric assessment (CGA), a core specialty of geriatric medicine, serves as a fundamental framework for the clinical identification of geriatric syndromes and multidisciplinary management. It is emerging as a key pathway to promote "healthy aging." Guided by this premise, this study aims to explore the application value of CGA in managing chronic diseases among older adults, with the goal of achieving full-cycle management for early detection, diagnosis, and treatment of chronic conditions in China's elderly population.
Henan Provincial People's Hospital is the lead sponsor of 63 studies on the registry; 33 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The study population consisted of patients with chronic diseases in the elderly who underwent comprehensive geriatric assessment and management. Chronic diseases in the elderly included but were not limited to chronic heart failure, chronic obstructive pulmonary disease, cognitive dysfunction, and so on.
Exclusion Criteria:
1. Presence of any condition/circumstance which in the opinion of the investigator could significantly limit the complete follow up of the patient (e.g. tourist, non-native speaker or does not understand the local language, psychiatric disturbances).
2. Presence of serious/severe co-morbidities in the opinion of the investigator which may limit short term (i.e. 6 month) life expectancy.
3. Current participation in a randomised interventional clinical trial.
The study population consisted of patients with chronic diseases in the elderly who underwent comprehensive geriatric assessment and management. Chronic diseases in the elderly included but were not limited to chronic heart failure, chronic obstructive pulmonary disease, cognitive dysfunction, and so on. We compared various biochemical indexes, cardiac function indexes, quality of life, and the occurrence of long-term adverse events before and after the comprehensive geriatric assessment and management.
Diagnostic Test: comprehensive geriatric assessment
The control group was composed of elderly subjects without evidence of chronic diseases. Chronic diseases was excluded by performing a complete medical history, a comprehensive physical examination, and an echocardiogram.
Diagnostic Test: comprehensive geriatric assessment
The comprehensive geriatric assessment (CGA) is a multi dimensional diagnostic process used to determine the medi cal, psychological, and functional capabilities of a frail elderly person to develop a coordinated and integrated plan for treat ment and long-term follow-up.
Major adverse events (MAE)
Major adverse events (MAE) in overall population, defined as composite of all-cause death, Heart Failure hospitalization, recurrent myocardial infarction, stroke, etc.
Time frame: These data is collected during follow-up visit at 3/6/12/24/36 months after discharge
Age for each participant
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Gender for each participant
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Height for each participant
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Weight for each participant
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Contact information for each participant
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Past Medical History including disease history, surgical history, and family medical history
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Lifestyle including smoking history and drinking, specify how many years smoking or drinking lasted and detail quantity per day
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：blood lipid
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：blood glucose
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：uric acid
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：urea
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：creatinine
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：C reactive protein
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：D-dimer
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
blood biochemical index：NT-proBNP
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Cardiac ultrasound
The whole results of echocardiography report will be recorded. The indicates which can reflect cardiac function including Left ventricular ejection fraction, left ventricular end diastolic diameter, E/A ratio of bicuspid valve will be used to calculate the association with metabolites.
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Drug treatment
Oral drug therapy, including antiplatelet drugs, antihypertensive drugs, lipid-lowering drugs, etc.
Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting
Comprehensive Geriatric Assessment: Frailty
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Sarcopenia
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Falls
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Disability
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Dysphagia
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Malnutrition
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Urinary incontinence
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Fecal incontinence
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Constipation
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Cognitive impairment
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Anxiety state
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Depressive state
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Sleep disorders
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Pain
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Social support
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
Comprehensive Geriatric Assessment: Home environment
Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment
No study locations are listed for this record.
Plan to share: No
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Henan Provincial People's Hospital