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Not yet recruitingNCT07007390Updated Jun 5, 2025

Systems Biology of Amyotrophic Lateral Sclerosis (ALS)

An observational study in ALS and ALS (Amyotrophic Lateral Sclerosis), sponsored by Viome. Not yet recruiting. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-05.

Sponsored by Viome · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
20
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this observational study is to identify molecular features in multiple clinical samples and/or the patient environment that are associated with ALS. Participants will collect biological samples and answer questionnaires regarding their health at each appointment with their ALS practitioner.

02

Conditions studied

  • ALS
  • ALS (Amyotrophic Lateral Sclerosis)
03

In context

Amyotrophic Lateral Sclerosis

978 studies on the registry are indexed under Amyotrophic Lateral Sclerosis; 277 are open to participants now.

This study's planned enrollment of 20 is below the median of 108 across 265 observational studies indexed under Amyotrophic Lateral Sclerosis.

Browse Amyotrophic Lateral Sclerosis studies →

Lead sponsor

Viome is the lead sponsor of 25 studies on the registry; 13 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

ALS cohort: Patients of Dr. Espíndola at UFSC Control cohort: Participants from the general population

Inclusion criteria

  • Patient of Dr. Espíndola at UFSC

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
20 participants (estimated)
Patient registry
No

Groups and cohorts

  • ALS Cohort

    Patients of Dr. Espíndola at UFSC that are diagnosed with ALS and meet the inclusion/exclusion criteria.

  • Control Cohort

    Those that meet the inclusion/exclusion criteria, do not have ALS, and generally are healthy.

06

What researchers measure

Primary outcomes

  1. Molecular features of biological samples that are predictive of ALS progression

    Time frame: We will collect samples and health data from each participant from the time of diagnosis to their death or study termination, whichever comes sooner. Specific time frame: We will collect outcome measures through study completion, an average of 3 years.

07

Study locations

No study locations are listed for this record.

08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Jun 2025; primary completion for Feb 2030, 56 months later.

Of 136 observational studies under Amyotrophic Lateral Sclerosis, half reached primary completion within 64 months of starting (the median), counting those still running; a quarter within 29 and three quarters within 114. This study's planned 56 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 28, 2025
First posted
Jun 5, 2025
StartEst.
Jun 1, 2025
Primary completionEst.
Feb 1, 2030
CompletionEst.
May 1, 2030
Last update
Jun 5, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 5, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07007390
Lead sponsor
Viome
Collaborators
Universidade Federal de Santa Catarina
Responsible party
Sponsor
First posted
Jun 5, 2025
Start date
Jun 1, 2025 (estimated)
Primary completion
Feb 1, 2030 (estimated)
Completion
May 1, 2030 (estimated)
Last update
Jun 5, 2025

Study contacts

Raquel Clinical Research Coordinator, BS
Contact
studies@viome.com
425-368-5248
Momo Chief Science Officer, Head of Clinical Research, PhD
Contact
studies@viome.com

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.

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