A Phase 1 interventional study of Risankizumab and Risankizumab in Healthy Volunteers, sponsored by AbbVie. Completed at 4 sites in United States. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-27.
Sponsored by AbbVie · Phase 1, Interventional, and Basic science
This study will assess the pharmacokinetics and relative Bioavailability of risankizumab following subcutaneous administration with an on-body injector relative to a prefilled syringe
AbbVie is the lead sponsor of 953 studies on the registry; 136 are open to participants now.
Of its 350 completed or terminated interventional studies of FDA-regulated products, 210 (60%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants will receive a Subcutaneous (SC) single dose of Risankizumab PFS on Day 1
Drug: Risankizumab
Participants will receive a Subcutaneous (SC) single dose of Risankizumab OBI on Day 1
Drug: Risankizumab
Subcutaneous (SC) Injection
On-Body Injector (OBI)
Maximum Observed Plasma Concentration (Cmax) of Risankizumab
Maximum observed plasma concentration (Cmax) of Risankizumab
Time frame: Up to Approximately 113 days
Time to Cmax (Tmax) of Risankizumab
Tmax of Risankizumab
Time frame: Up to Approximately 113 days
Apparent Terminal Phase Elimination Rate Constant (β) of Risankizumab
Apparent terminal phase elimination rate constant (β) of Risankizumab
Time frame: Up to Approximately 113 days
Terminal Phase Elimination Half-life (t1/2) of Risankizumab
Terminal phase elimination half-life (t1/2) of Risankizumab
Time frame: Up to Approximately 113 days
Area Under the Plasma Concentration-Time Curve (AUC) From Time 0 to the Last Measurable Concentration (AUCt) of Risankizumab
AUCt of Risankizumab
Time frame: Up to Approximately 113 days
Area Under the Plasma Concentration-Time Curve (AUC) From Time 0 to Infinity (AUCinf) of Risankizumab
AUCinf of Risankizumab
Time frame: Up to Approximately 113 days
Number of Anti-drug antibodies (ADA)
Incidence of anti-drug antibodies
Time frame: Up to Approximately 113 days
Number of Participants Experiencing Adverse Events
An adverse event is defined as any untoward medical occurrence in a patient or clinical investigation participant administered a pharmaceutical product and which does not necessarily have a causal relationship with this treatment
Time frame: Up to Approximately 113 days
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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