CClinicalTrials.gg
CompletedNCT07004491PainUpdated Oct 5, 2026

Comparison Of Different Physiotherapy Methods In People With Non-Specific Neck Pain

An interventional study of Conventional therapy and Conventional therapy+ Mulligan mobilization in Neck Pain, sponsored by Istanbul Medipol University Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 25 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-05.

Sponsored by Istanbul Medipol University Hospital · Not applicable, Interventional, and Treatment

Updated Oct 5, 2026Now CompletedEnrollment updatedGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
45
Allocation
Randomized
Ages
25 Years to 55 Years
Sex
All
01

Study summary

The study will include 45 people between the ages of 25-55 with non-specific neck pain. The patients will be randomly divided into three groups. Group 1 will receive 5 minutes of ultrasound, 20 minutes of transcutaneous electrical nerve stimulation (TENS), and hot pack application. Group 2 will receive 5 minutes of ultrasound, 20 minutes of transcutaneous electrical nerve stimulation (TENS), and hot pack application in addition to the Mulligan mobilization technique. Group 3 will receive 5 minutes of ultrasound, 20 minutes of transcutaneous electrical nerve stimulation (TENS), and hot pack application in addition to graston treatment for 5 minutes to the upper and lower trapezius, rhomboid major and minor muscles.

Read the detailed description

The study will include 45 people between the ages of 25-55 with non-specific neck pain. The patients will be randomly divided into three groups. Group 1 will receive 5 minutes of ultrasound, 20 minutes of transcutaneous electrical nerve stimulation (TENS), and hot pack application. Group 2 will receive 5 minutes of ultrasound, 20 minutes of transcutaneous electrical nerve stimulation (TENS), and hot pack application in addition to the Mulligan mobilization technique. Group 3 will receive 5 minutes of ultrasound, 20 minutes of transcutaneous electrical nerve stimulation (TENS), and hot pack application in addition to graston treatment for 5 minutes to the upper and lower trapezius, rhomboid major and minor muscles. The patients will receive treatments 3-4 times a week for 4 weeks, for a total of 10 sessions. VAS, neck joint range of motion, functional status and disability level neck pain and disability scale and SF-36 will be used as evaluation measurements.

02

Conditions studied

  • Neck Pain

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Keywords

  • Non specific neck pain
  • physiotherapy applicaitons
  • pain
03

In context

Neck Pain

1,231 studies on the registry are indexed under Neck Pain; 254 are open to participants now.

This study's enrollment of 45 is below the median of 52 across 1,004 interventional studies indexed under Neck Pain.

Browse Neck Pain studies →

Lead sponsor

Istanbul Medipol University Hospital is the lead sponsor of 350 studies on the registry; 58 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
25 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Patients diagnosed with non-specific neck pain by a doctor
  • aged between 25-55
  • who have had pain in their neck for at least 2 weeks will be included in the study.

Exclusion criteria

Exclusion Criteria:

  • Neurological disease
  • Manual therapy contraindication such as osteoporosis, spinal infection
  • Spondyloarthropathy, disc herniation
  • People with contraindications to the Graston technique such as neoplastic disorders, anticoagulant drug use, uncontrolled hypertension or general infection will not be included in the study
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
45 participants (actual)

Study arms

  • Experimental
    First Intervention

    5 minutes of Ultrasound, 20 minutes of Transcutaneous Electrical Nerve Stimulation (TENS) and hot pack application will be applied.

    Other: Conventional therapy

  • Experimental
    Second Intervention

    In addition to 5 minutes of Ultrasound, 20 minutes of Transcutaneous Electrical Nerve Stimulation (TENS) and hot pack application, Mulligan mobilization technique will be applied. Continuous apophyseal shifting technique will be applied as mobilization. Mobilization will be applied in 3 sets of 4-5 repetitions.

    Other: Conventional therapy+ Mulligan mobilization

  • Experimental
    Third Intervention

    In addition to 5 minutes of Ultrasound, 20 minutes of Transcutaneous Electrical Nerve Stimulation (TENS) and hot pack application, Graston treatment will be applied to the upper and lower trapezius, rhomboid major and minor muscles for 5 minutes.

    Other: Conventional therapy+ Graston

Interventions

  • OtherConventional therapy

    Ultrasound, Transcutaneous Electrical Nerve Stimulation (TENS) and hot pack application

  • OtherConventional therapy+ Mulligan mobilization

    Conventional therapy+ Mulligan mobilization

  • OtherConventional therapy+ Graston

    Conventional therapy+ Graston application

06

What researchers measure

Primary outcomes

  1. Visucal Analog scale

    The Visual Analog Scale (VAS) (0-10 cm), which is found to be valid, reliable and sensitive in patients with neck pain, will be used to assess pain. O means no pain; 10 means severe pain.

    Time frame: 10 minutes

  2. Joint range of motion

    The patients' neck joint range of motion will be measured with a standard goniometer.

    Time frame: 20 minutes

  3. Quality of life (SF-36)

    SF-36 will be used to assess the participants' quality of life. The 36-question questionnaire is divided into 8 groups: physical role functioning, emotional role functioning, bodily pain, energy, social role functioning, mental health and general health perception. Each category is scored between 0-100 and higher scores indicate better quality of life

    Time frame: 15 minutes

  4. The neck disability scale

    Functional status and disability level will be assessed with the neck pain and disability scale.The neck disability scale will be used to assess how the participants' daily lives are affected by neck pain. The total score of the scale ranges from 0 to 35, with higher scores indicating higher levels of disability

    Time frame: 15 minutes

07

Study locations

1 site
  • Istanbul Medipol University
    Istanbul, Turkey (Türkiye)
08

References and documents

Publications

  • Mahmood T, Afzal W, Ahmad U, Arif MA, Ahmad A. Comparative effectiveness of routine physical therapy with and without instrument assisted soft tissue mobilization in patients with neck pain due to upper crossed syndrome. J Pak Med Assoc. 2021 Oct;71(10):2304-2308. doi: 10.47391/JPMA.03-415. PubMed 34974559 ↗

Individual participant data

Plan to share: No — We can share IPD if it is need.

09

Updates

1 registry update since Sep 25, 2026
Status
Active, not recruiting→Completed
changed Oct 5, 2026
Show all 1 update
  1. Oct 5, 2026
    Active, not recruiting→Completed
    + 4 other changes: index terms, verification date, date precision and site details

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07004491
Lead sponsor
Istanbul Medipol University Hospital
Responsible party
merve yilmaz menek (Principal Investigator, Istanbul Medipol University Hospital) — Principal investigator
First posted
Jun 4, 2025
Start date
May 26, 2025
Primary completion
Jul 26, 2025
Completion
Sep 30, 2025
Last update
Oct 5, 2026

Study contacts

MERVE YILMAZ MENEK, Assoc. Prof.
principal investigator · Medipol University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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