An interventional study of Groin closure with PDS suture and Groin closure suture material in Vascular Diseases, sponsored by The Cleveland Clinic. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-03.
Sponsored by The Cleveland Clinic · Not applicable, Interventional, and Treatment
This is a randomized controlled trial comparing groin closure after vascular intervention with Vicryl suture versus PDS (polydioxanone) suture. This will be a single center trail performed at CCF main campus. Patients will be enrolled in a prospective fashion and will be randomized 1:1 to either PDS or Vicryl closure. Patients undergoing bilateral groin exposure will be randomized to receive both closure types to either groin.
Previous research has provided insights into the properties of various suture materials, yet there remains a gap in our understanding of their relative effectiveness in groin closure specifically within the context of vascular surgery. The lack of definitive evidence on whether Vicryl or PDS (polydioxanone) sutures offer superior outcomes necessitates further investigation. This study aims to address this gap by conducting a head-to-head comparison of these sutures, focusing on their impact on postoperative groin complications.
This is a randomized controlled trial comparing groin closure after vascular intervention with Vicryl versus PDS. This will be a single center trail performed at CCF main campus. Patients will be enrolled in a prospective fashion and will be randomized 1:1 to either PDS or Vicryl closure. Patients undergoing bilateral groin exposure will be randomized to receive both closure types to either groin.
The primary objective of this randomized controlled trial (RCT) is to evaluate the effectiveness of Vicryl versus PDS sutures in reducing groin complications following vascular surgery.
1,027 studies on the registry are indexed under Vascular Diseases; 167 are open to participants now.
This study's planned enrollment of 259 is above the median of 78 across 639 interventional studies indexed under Vascular Diseases.
Browse Vascular Diseases studies →The Cleveland Clinic is the lead sponsor of 818 studies on the registry; 118 are open to participants now.
Of its 89 completed or terminated interventional studies of FDA-regulated products, 72 (81%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Vascular intervention access site closed with PDS suture
Procedure: Groin closure with PDS suture
Vascular intervention access site closure with Vicryl suture
Procedure: Groin closure suture material
Closure of the groin will be performed with PDS suture
Closure of the groin will be performed with Vicryl suture
Rate of groin complication
Number of occurrence of the access site complication
Time frame: 30 days and 1 year
Plan to share: No
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