An observational study in Carpometacarpal (CMC) Joint Arthritis, Ganglion Cyst and De Quervain Disease, sponsored by Fatih Sultan Mehmet Training and Research Hospital. Completed at 1 site in Turkey. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-05-20.
Sponsored by Fatih Sultan Mehmet Training and Research Hospital · Observational
This study aims to investigate the correlation between ultrasonographic and clinical findings in dorsoradial wrist pain. There are several etiologies for dorsoradial wrist pain, including carpometacarpal joint arthritis, De Quervain's tenosynovitis, proximal and distal intersection syndrome, Wartenberg syndrome, and ganglion cysts. In these clinical scenarios, certain physical examination tests are utilized, such as the Finkelstein test for De Quervain's tenosynovitis; however, this test may also yield positive results in cases of severe joint arthritis. Ultrasonography is proposed as a complementary tool for differential diagnosis. The investigators aim to examine the correlation between clinical test results and ultrasonographic parameters such as tendon thickness in the first extensor compartment, carpometacarpal joint synovitis, cortical irregularities, and the presence of osteophytes. Functional status will be assessed using the QuickDASH and FIHOA questionnaires.
In the assessment of the first carpometacarpal (CMC) joint, the following ultrasonographic parameters will be evaluated: synovitis, presence of osteophytes, joint surface irregularity, and Doppler signal activity. Additionally, conventional hand radiographs of all participants will be reviewed to support the imaging findings.
For the evaluation of De Quervain's tenosynovitis, tendon sheath thickness, tendon cross-sectional area, and intratendinous Doppler activity will be measured. At the anatomical intersection zones of the first dorsal compartment, the presence of peritendinous fluid and associated Doppler activity will also be assessed to identify potential sites of friction or inflammation.
Assessment of the superficial radial nerve will include measurement of its cross-sectional area. A cross-sectional area exceeding one square millimeter will be considered indicative of possible neuropathy.
136 studies on the registry are indexed under Ganglion Cysts; 28 are open to participants now.
This study's enrollment of 45 is close to the median of 44 across 28 observational studies indexed under Ganglion Cysts.
Browse Ganglion Cysts studies →Fatih Sultan Mehmet Training and Research Hospital is the lead sponsor of 118 studies on the registry; 34 are open to participants now.
Counted across the registry records on this site, refreshed daily.
patients who referred physical theraphy and rehabilitation and orthopedia clinics with dorsoradial wrist and thumb pain
Exclusion Criteria:
ultrasonographic examination
Odds Ratio of First Extensor Compartment Tendon Sheath Thickness Associated with De Quervain Disease
To quantify the association between increased tendon sheath thickness and clinical diagnosis of De Quervain tenosynovitis using logistic regression analysis.
Time frame: At the time of enrollment
Odds Ratio of Synovial Hypertrophy in CMC Joint Associated with Carpometacarpal Arthritis
To assess the strength of association between ultrasonographic synovial hypertrophy and clinical diagnosis of carpometacarpal joint arthritis.
Time frame: At the time of enrollment
Sensitivity of Ultrasonographic Parameters for Diagnosing Dorsoradial Wrist Pathologies
To assess the diagnostic sensitivity of individual ultrasonographic findings (e.g., tendon sheath thickness, synovial hypertrophy) for detecting De Quervain tenosynovitis and CMC arthritis.
Time frame: At the time of enrollment
Specificity of Ultrasonographic Parameters for Diagnosing Dorsoradial Wrist Pathologies
To assess the diagnostic specificity of individual ultrasonographic findings for identifying De Quervain tenosynovitis and CMC arthritis.
Time frame: At the time of enrollment
Plan to share: Undecided
This study is completed, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
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Fatih Sultan Mehmet Training and Research Hospital