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Not yet recruitingNCT06969911Updated May 14, 2025

Clinical Evaluation of CAD/CAM vs. Conventional Veneer Restorations

An interventional study of Laminate veneer CAD/CAM and Laminate Veneer Convetional in Malformed Tooth, sponsored by Heinrich-Heine University, Duesseldorf. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-05-14.

Sponsored by Heinrich-Heine University, Duesseldorf · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The aim of the study is to clinically evaluate tooth-supported veneer restorations fabricated using the CAD/CAM process in comparison to conventionally manufactured pressed veneers on anterior teeth and to assess their long-term performance. Survival and success rates of anterior veneer restorations, as well as patient satisfaction, will be evaluated.

Read the detailed description

Functional and aesthetic complaints caused by congenital malformations and acquired tooth damage are widely spread. Discomfort involves reduced chewing ability, phonetic problems, hypersensitivity and aesthetic impairments.

Conventionally fabricated all-ceramic veneer restorations reveal a long history of clinical success in minimally invasive rehabilitation of the anterior dentition. Nevertheless, conventional manufacturing techniques are prone to fabrication mistakes and must be handled by experienced dental technicians and dentists which results in very high fabrication costs. Therefore, access to minimally invasive restorations is currently restricted for most of the patients. Innovative CAD/CAM techniques have revolutionised restorative treatment options over the last decades and have made all-ceramic restorations more affordable for patients. With further improvements of the CAD/CAM milling devices the machinability of high-strength glass ceramic is now possible.

The aim of both treatment procedures will be to avoid any extensive additional tooth structure removal, to provide long-term survival and success of the integrated restorations and to improve patient´s satisfaction. Up to now scientific evidence on the clinical performance of CAD/CAM fabricated veneers is very limited. Aim of this trial is to evaluate if the clinical performance of anterior restorations after minimally invasive therapeutic intervention with CAD/CAM veneers compared to conventionally fabricated veneers. Functional and aesthetic treatment results will be assessed for five years and evaluated with regard to failure and succes veneer restorations as well as patient satisfaction.

02

Conditions studied

  • Malformed Tooth
03

In context

Lead sponsor

Heinrich-Heine University, Duesseldorf is the lead sponsor of 174 studies on the registry; 52 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients ≥ 18 years of age
  • Patients that reveal indication for a minimum of 2 and a maximum of 6 anterior veneer restorations

Exclusion criteria

Exclusion Criteria:

  • Patients that reveal multiple missing teeth, poor oral hygiene, pronounced parafunctions or with allergies to any of the applied materials
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Sham comparator
    Control Group: Conventional veneer restoration

    Therapeutic intervention with minimally invasive traditionally fabricated all-ceramic anterior veneers.

    Procedure: Laminate Veneer Convetional

  • Active comparator
    Study Group: CAD/CAM veneer restoration

    Therapeutic intervention with minimally invasive CAD/CAM all-ceramic anterior veneers.

    Procedure: Laminate veneer CAD/CAM

Interventions

  • ProcedureLaminate veneer CAD/CAM

    Minimally invasive therapeutic intervention with CAD/CAM veneers

  • ProcedureLaminate Veneer Convetional

    Minimally invasive therapeutic intervention with CAD/CAM veneers

06

What researchers measure

Primary outcomes

  1. Prosthetic survival time

    The primary objective is to compare the prosthetic survival time of the restorations (conventional vs. CAD/CAM veneers).

    Time frame: 5 Years

Secondary outcomes

  1. Prosthetic success

    The secondary objectives are to compare the prosthetic success of the restorations (conventional vs. CAD/CAM veneers), the documentation of failures such as fractures and the assessment of patient centered satisfaction.

    Time frame: 5 Years

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 14, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06969911
Lead sponsor
Heinrich-Heine University, Duesseldorf
Responsible party
Sponsor
First posted
May 14, 2025
Start date
May 5, 2025 (estimated)
Primary completion
Mar 31, 2032 (estimated)
Completion
Mar 31, 2032 (estimated)
Last update
May 14, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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