An observational study in Alzheimer's Disease, Hippocampus and Brain Atrophy, sponsored by Centre Hospitalier de Saint-Denis. Completed at 1 site in France. Per ClinicalTrials.gov, last updated 2025-05-11.
Sponsored by Centre Hospitalier de Saint-Denis · Observational
This study aims to better understand Alzheimer's disease by looking at brain scans, specifically MRI images, to detect early signs of brain changes linked to the disease. Researchers are focusing on the hippocampus, a part of the brain that shrinks in people with Alzheimer's. The study will also explore other brain changes that often happen alongside hippocampal shrinkage. By analyzing these brain images, the study hopes to find ways to diagnose Alzheimer's earlier and more accurately using advanced imaging techniques.
3,678 studies on the registry are indexed under Alzheimer Disease; 872 are open to participants now.
This study's enrollment of 85 is below the median of 200 across 751 observational studies indexed under Alzheimer Disease.
Browse Alzheimer Disease studies →Centre Hospitalier de Saint-Denis is the lead sponsor of 42 studies on the registry; 19 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Participants will be selected from a retrospective cohort of patients who underwent brain MRI scans (3D T1 Bravo and Cube FLAIR sequences) between January 2018 and June 2022. The study population includes two groups: patients diagnosed with Alzheimer's disease based on clinical and biological assessments, and cognitively healthy individuals with no history of neurological or psychiatric disorders, serving as controls.
Exclusion Criteria:
Alzheimer's patients
Unreached witnesses
Hippocampal Volume Measured by 3D MRI
Objective volumetric measurement of the right and left hippocampus using 3D T1 Bravo MRI sequences, allowing quantification of hippocampal atrophy.
Time frame: Retrospective analysis between January 2018 and June 2022
Plan to share: No
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This study is completed, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier de Saint-Denis