A Phase 4 interventional study of Antivet and opalustre in Enamel Discoloration and Fluorosis, Dental, sponsored by Cairo University. Not yet recruiting. Open to participants aged 15 Years to 45 Years. Per ClinicalTrials.gov, last updated 2025-04-29.
Sponsored by Cairo University · Phase 4, Interventional, and Treatment
compare the clinical performance of different concentrations of hydrochloric acid based as micro abrasive kits in management of patients with mild to moderate fluorosis over 6month follow up .
microabrasion is a permanent cosmetic dentistry treatment indeed to preserve the health of all part of any defect in enamel.
Patients who wanted to change the appearance of their stained teeth Males or females. Patients with three or more stained incisors and canines Patients willing and able to attend periodic follow-up visits Patient concerning with oral health. Co-operative patients who show interest to participate in the study.
Exclusion Criteria:
Patients with known allergic or adverse reaction to the tested materials. Smoking habit Patients having Poor oral hygiene Patients with special health care needs or any systemic disease that may affect treatment Patients participating in other dental studies. Patients suffering from white spot lesion, hypoplasia, amelogenesis imperfecta, dentinogenesis imperfecta, or badly broken and missing teeth due to MIH.
Participants who had a history of dental bleaching.
Complete stain removal from the Enamel Use a compact cotton swab (3 mm) to apply Antivet solution (Dental Continental, México)to the stained dental piece according to manufacturer's instructions. Replace the swab as it becomes stained and continue until the stain is removed. " This may take 1-5 minutes per tooth, but do not exceed 15 minutes in total. " We will keep the tooth moist during the process for effective results and avoid reusing stained cotton swab. Then we will apply the neutralizing solution to the tooth with a brush or micro brush, ensuring it reaches the gingival margin. Leave it on for 2 minutes. Once the antivet solution is neutralized, rinse the area and remove the rubber dam.
Drug: Antivet
Complete stain removal from the Enamel. Product will be applied to the surface with a 1 mm thick layer; ten applications of 60s to help penetration of the gel into the enamel. Using an abrasive rubber cup (OpalCup™ Ultradent) in contra-angle low-speed handpiece at low revolution. Then will be rinsed with injectable water for 30 seconds between each application
Drug: opalustre
Complete stain removal from the Enamel-Use a compact cotton swab (3 mm) to apply Antivet solution (Dental Continental, México)to the stained dental piece according to manufacturer's instructions.-Replace the swab as it becomes stained and continue until the stain is removed. " This may take 1-5 minutes per tooth, but do not exceed 15 minutes in total. " - We will keep the tooth moist during the process for effective results and avoid reusing stained cotton swab.-Then we will apply the neutralizing solution to the tooth with a brush or micro brush, ensuring it reaches the gingival margin. Leave it on for 2 minutes.-Once the antivet solution is neutralized, rinse the area and remove the rubber dam.
Complete stain removal from the Enamel. Product will be applied to the surface with a 1 mm thick layer; ten applications of 60s to help penetration of the gel into the enamel.- Using an abrasive rubber cup (OpalCup™ Ultradent) in contra-angle low-speed handpiece at low revolution.- Then will be rinsed with injectable water for 30 seconds between each application.
Clinical assessment of treatment success
Enamel discoloration or texture by Spectrophotometer Vita EasyShade When totally removed of fluorotic white spots = success \& when stains doesn't removed and surface irregular = failure
Time frame: T( Time ) T0(base line )=Immediately , T1 = 3 Months , T2 = 6 Month
Clinical evaluation of Sensitivity
Patient reported outcome measures by visual analog scale (VAS) Is used to describe sensitivity by patient themselves in scores as ( o : no sensitivity) ( 10 : highly sensitive )
Time frame: Time frame : T( Time ) T0(base line )=Immediately , T1 = 3 Months , T2 = 6 Month
Patient satisfaction with the Treatment.
Patient reported outcome measures by 4-point Likert scale used to describe patient satisfaction with treatment as \[(a) "yes, very satisfied", (b) "yes, mostly satisfied", (c) "less satisfied", (d) "not at all satisfied"\].
Time frame: Time frame : T( Time ) T0(base line )=Immediately , T1 = 3 Months , T2 = 6 Month
No study locations are listed for this record.
Plan to share: Yes
No publications or documents are linked to this record.
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Cairo University