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Active, not recruitingNCT06949371ChronotypeUpdated May 30, 2025

Investigation of the Effects of Chronotype Differences on Balance and Muscle Strength in Young Adults

An interventional study of Morning chronotype and Evening chronotype in Chronotype, sponsored by Istanbul Medipol University Hospital. Active, not recruiting at 1 site in Turkey. Open to participants aged 45 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-05-30.

Sponsored by Istanbul Medipol University Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jun 2025, 1 year 3 months ago, but the record still lists the study as active, not recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
45 Years to 65 Years
Sex
All
01

Study summary

The aim of this study is to investigate the effects of chronotype differences on balance and muscle strength in young adults. Chronotypes of all participants will be determined using the Morningness-Eveningness Questionnaire. All assessment measurements determined for young adult individuals will be performed first at 09:00 in the morning and then again at 19:00 in the evening.

Read the detailed description

The aim of this study is to investigate the effects of chronotype differences on balance and muscle strength in young adults. Inclusion criteria are being between 45-65 years old, not having any neurological or orthopedic disorders, not having a vestibular disease that causes balance problems. Exclusion criteria are trauma history, anatomical deformities and skeletal system fractures, having a previous injury, and the presence of pain that will prevent participation in the tests. Chronotypes of all participants will be determined using the Morningness-Eveningness Questionnaire. All assessment measurements determined for young adult individuals will be performed first at 09:00 in the morning and then again at 19:00 in the evening. Muscle strength and balance assessments made in the morning and evening will be compared. Chronotypes of the participants will be evaluated with the Morningness-Eveningness Questionnaire, their balance will be evaluated with the One-Legged Standing Test, lower extremity muscle strength with a myometer, and their functionality will be evaluated with the Timed Stand-Up-Sit Test and the 30-Second Sit-Up Test.

02

Conditions studied

  • Chronotype

Keywords

  • Chronotype
  • muscle strength
  • balance
  • functionality
03

In context

Lead sponsor

Istanbul Medipol University Hospital is the lead sponsor of 350 studies on the registry; 58 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
45 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • being between 45-65,
  • not having any neurological or orthopedic disorder,
  • not having a vestibular disease that causes balance problems.

Exclusion criteria

Exclusion Criteria:

  • trauma history,
  • anatomical deformities and skeletal system fractures,
  • having a previous injury and the presence of pain that would prevent participation in the tests.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    Morning chronotype group

    All assessment measurements determined for individuals with morning chronotype will be performed first at 09:00 in the morning and then again at 19:00 in the evening.

    Other: Morning chronotype

  • Experimental
    Evening chronotype group

    All assessment measurements determined for individuals with evening chronotype will be performed first at 09:00 in the morning and then again at 19:00 in the evening.

    Other: Evening chronotype

Interventions

  • OtherMorning chronotype

    All assessment measurements determined for individuals with morning chronotype will be performed first at 09:00 in the morning and then again at 19:00 in the evening. Muscle strength balance assessments performed in the morning and evening will be compared.

  • OtherEvening chronotype

    All assessment measurements determined for individuals with evening chronotype will be performed first at 09:00 in the morning and then again at 19:00 in the evening. Muscle strength balance assessments performed in the morning and evening will be compared.

06

What researchers measure

Primary outcomes

  1. Morningness-Eveningness Questionnaire

    A questionnaire form that determines morningness and eveningness types will be used to subjectively evaluate circadian rhythm. defi - nitely morning type (70-86), moderately morning type (59-69), neither type (42-58), moderately evening type (31-41), and defi nitely evening type (16-30).

    Time frame: 20 minutes

  2. Single-leg standing test

    This test measures a person's standing ability and balance.

    Time frame: 20 minutes

  3. Muscle strength test

    Myometry will be used to objectively measure the strength of the quadriceps and hamstring muscles. Myometry is an evaluation method that objectively evaluates muscle strength and provides more sensitive results than manual muscle testing.

    Time frame: 20 minutes

  4. Timed up and go testTest:

    A simple screening test that provides a sensitive and specific measure of fall risk and balance in older adults.

    Time frame: 20 minutes

  5. 30 Second Sit-to-Stand Test

    A test that evaluates the participant's sit-to-stand activity, lower extremity muscle strength and balance status.

    Time frame: 20 minutes

07

Study locations

1 site
  • Istanbul Medipol University
    Istanbul, Turkey
08

References and documents

Publications

  • Facer-Childs ER, Boiling S, Balanos GM. The effects of time of day and chronotype on cognitive and physical performance in healthy volunteers. Sports Med Open. 2018 Oct 24;4(1):47. doi: 10.1186/s40798-018-0162-z. PubMed 30357501 ↗

Individual participant data

Plan to share: No — We can share IPD when it isi necessary.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06949371
Lead sponsor
Istanbul Medipol University Hospital
Responsible party
merve yilmaz menek (Principal Investigator, Istanbul Medipol University Hospital) — Principal investigator
First posted
Apr 29, 2025
Start date
Apr 22, 2025
Primary completion
Jun 10, 2025 (estimated)
Completion
Jul 10, 2025 (estimated)
Last update
May 30, 2025

Study contacts

MERVE YILMAZ MENEK, Assoc. Prof.
principal investigator · Medipol University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.

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