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RecruitingNCT06930508Updated Aug 6, 2026

Bringing Medicines for HIV Prevention to a Family Planning Clinic

An interventional study of Patient participant screening and Physician participant training in HIV and PrEP, sponsored by Women and Infants Hospital of Rhode Island. Recruiting at 1 site in United States. Open to participants aged 16 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-06.

Sponsored by Women and Infants Hospital of Rhode Island · Not applicable, Interventional, and Screening

Phase
Not applicable
Study type
Interventional
Enrollment
83
Allocation
Non-randomized
Ages
16 Years and older
Sex
All
01

Study summary

The goal of this clinical trial is to understand what patients and physicians think about providing medications to prevent HIV transmission to patients in a family planning clinic. These medications are known as pre-exposure prophylaxis, or PrEP. The main questions to answer are:

  1. Do patients find it acceptable to be asked about, and offered, PrEP during their visit to a family planning clinic?
  2. What things make it easier or harder to ask about PrEP in a family planning clinic setting?
  3. What things make it easier or harder to begin PrEP in a family planning clinic setting?

Patient participants:

  1. Will receive standardized counseling about PrEP.
  2. Will have the opportunity to begin PrEP as part of their routine, ongoing care.
  3. Will be asked to complete a survey about their experiences.

Physician participants:

  1. Will receive standardized education about PrEP.
  2. Will talk to patient participants about PrEP, and support patient participants who want to begin PrEP.
  3. Will be asked to complete pre-and post-study surveys about their experiences.
  4. May be asked to complete a post-study in-depth interview about their experiences.
Read the detailed description

In the proposed pilot study, the investigators' goal is to improve community health resources available to Rhode Islanders to lower their risk of HIV acquisition, via the following specific aims:

  1. Evaluate the patient acceptability of HIV pre-exposure prophylaxis (PrEP) eligibility screening and initiation in an ob/gyn-staffed family planning clinic.
  2. Assess the barriers, facilitators, and feasibility of PrEP eligibility screening in an ob/gyn-staffed family planning clinic.
  3. Assess the barriers, facilitators, and feasibility of delivery and uptake of PrEP in an ob/gyn-staffed family planning clinic.

Overall, the investigators' expected outcome is to have exploratory data to inform a scalable intervention to implement PrEP access, which can be deployed in family planning clinic settings, and which is designed in accordance with acceptability and feasibility data from patients and providers. Since the existing data suggest that ob/gyn-staffed family planning clinics are an ideal site both as a catchment area for patients who are at higher risk for HIV acquisition, and in terms of technical capacity and provider skill set, the next step to expand PrEP service delivery in these settings is to assess the barriers and facilitators to such care, in order to meet patients where they are, with the care they need. The goal is to situate the protocol to fit into the usual clinical workflow of a busy family planning clinic.

The investigators will develop and implement a standardized PrEP eligibility screening instrument and initiation protocol, based on CDC guidelines. The investigators will survey patient and physician participants about feasibility and acceptability of study procedures. Patient participants will be approached by a research assistant, who will inform eligible individuals about the purpose, risks, and benefits of the study. The research assistant will obtain informed consent from participants. Physicians will then screen participants for PrEP eligibility per protocol, and will offer initiation of PrEP. These medications are not investigational, are part of standard of care STI prevention, and are not themselves the primary subject of this study.

The investigators' primary data collection will be via survey. Patient participants will receive a $25 gift card for completing the post-intervention survey. Physician participants will receive pre- and post-study surveys, and a subgroup will participate in focused interviews.

There is no control arm in this study. The alternative to participation in this study is to simply undergo (or provide) routine care in the investigators' Family Planning Clinic, which does not currently include PrEP provision - though, as described above, such care is within the scope of routine care in ob/gyn settings.

02

Conditions studied

  • HIV
  • PrEP

Keywords

  • HIV PrEP screening
  • HIV PrEP initiation
  • ob/gyn
03

Who can participate

Ages eligible
16 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

This study will include patient participants who:

  • Are age 16 or older
  • Are presenting for care at the Women and Infants Hospital of Rhode Island Family Planning Clinic
  • Speak English or Spanish
  • Have decisional capacity

This study will exclude patient participants who:

- Are currently seeking abortion care

This study will include physician participants who:

- Provide care at the Women and Infants Hospital of Rhode Island Family Planning Clinic

This study will not have any specific exclusion criteria for physician participants.

04

Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
83 participants (estimated)

Study arms

  • Experimental
    Patient Participant

    Behavioral: Patient participant screening

  • Experimental
    Physician Participant

    Behavioral: Physician participant training

Interventions

  • BehavioralPatient participant screening

    Patient participants will be provided with the standardized PrEP screening and initiation protocol.

  • BehavioralPhysician participant training

    Physician participants will be trained in the investigators' standardized PrEP screening and initiation protocol.

05

What researchers measure

Primary outcomes

  1. Acceptability of Intervention Measure

    A validated measure of acceptability, administered via questionnaire. 4 Likert scale items. Item score range 1-5. Higher scores reflect higher acceptability.

    Time frame: Up to hour 6 for patient participants; Up to month 12 for physician participants

  2. Feasibility of Intervention Measure

    A validated measure of feasibility, administered via questionnaire. 7-12 Likert scale items. Item score range 1-5. Higher scores reflect higher feasibility.

    Time frame: Up to hour 6 for patient participants; Up to month 12 for physician participants

  3. Intervention Appropriateness Measure

    A validated measure of appropriateness, administered via questionnaire. 4 Likert scale items. Item score range 1-5. Higher scores reflect higher appropriateness.

    Time frame: Up to hour 6 for patient participants; Up to month 12 for physician participants

06

Study locations

1 of 1 sites recruiting
  • Women and Infants Hospital of Rhode Island
    Providence, Rhode Island 02905, United States
    Recruiting
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT06930508
Lead sponsor
Women and Infants Hospital of Rhode Island
Collaborators
Advance RI CTR
Responsible party
Sponsor
First posted
Apr 16, 2025
Start date
May 28, 2026
Primary completion
Oct 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Aug 6, 2026

Study contacts

Benjamin P Brown, MD, MS
Contact
benjamin_brown@brown.edu
401-274-1122 ext. 41501
Erica J Hardy, MD, MMSc, MA
Contact
erica_hardy@brown.edu
401-453-7950

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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