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Not yet recruitingNCT06918353Updated Apr 11, 2025

The Severity Assessment Model for AECOPD With Combination of Disease and Syndrome

An observational study in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, sponsored by Henan University of Traditional Chinese Medicine. Not yet recruiting at 1 site in China. Per ClinicalTrials.gov, last updated 2025-04-11.

Primary conditionnone(registry's first term: Syndrome)No conditionIs this wrong?Syndrome describes something many studies share rather than a condition a study is about. The study names no condition we can place it under, so it is not compared with other studies by condition.

Sponsored by Henan University of Traditional Chinese Medicine · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
1,500
Sex
All
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Study summary

The establishment of the AECOPD severity assessment model can quickly and accurately evaluate the condition, which is of great significance for standardizing diagnosis and treatment, improving efficacy, and improving prognosis. At the same time, it can provide ideas and methods for the research of disease assessment models in related fields.

Read the detailed description

Accurate assessment of the condition is the prerequisite and basis for standardized clinical treatment. Traditional Chinese medicine has shown good efficacy and advantages in treating AECOPD, but currently there is no ideal standard for judging the severity, nor is there an accurate, practical, and TCM specific disease assessment tool. Therefore, this project integrates multidimensional variables of traditional Chinese and Western medicine, and intends to conduct research on the construction of a disease syndrome combined AECOPD disease assessment model through literature review, expert consultation, clinical investigation, and machine learning algorithms, and establish preliminary grading standards for the severity of AECOPD disease. Ultimately, it provides ideas and methods for the rapid and accurate assessment of AECOPD, standardized diagnosis and treatment, improved efficacy, improved prognosis, and research on disease assessment models in related fields.

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Conditions studied

  • Acute Exacerbation of Chronic Obstructive Pulmonary Disease

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Keywords

  • Acute Exacerbation of Chronic Obstructive Pulmonary Disease
  • Severity Assessment Model
  • Combination of Disease and Syndrome
  • Classification and Regression Trees
  • Artificial Neural Network
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In context

Lead sponsor

Henan University of Traditional Chinese Medicine is the lead sponsor of 55 studies on the registry; 31 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Meets AECOPD diagnostic criteria.
  • Voluntarily participate in the research and sign the consent form

Exclusion criteria

Exclusion Criteria:

  • Individuals with severe mental disorders and cognitive impairments who are unable to communicate normally
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Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
1,500 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes

Groups and cohorts

  • AECOPD Patients

    Diagnostic Test: Diagnosis and Severity Grading of AECOPD Disease

Interventions

  • Diagnostic testDiagnosis and Severity Grading of AECOPD Disease

    Diagnosis and severity grading of AECOPD disease, as well as assessment of traditional Chinese medicine syndromes

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What researchers measure

Primary outcomes

  1. Clinical Investigation Questionnaire on Influencing Factors of the Severity of AECOPD

    The influencing factors of the severity of AECOPD were evaluated through clinical investigation questionnaires. Questionnaire Title: Clinical Investigation Questionnaire on Influencing Factors of AECOPD Severity. The questionnaire adopts the scoring method, which is divided into "very unimportant", "not important", "average", "important" and "very important", and the corresponding values are assigned as 1, 2, 3, 4 and 5 respectively.The higher the score is, the more significant the result is.

    Time frame: 24 hours

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Study locations

1 site
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 11, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06918353
Lead sponsor
Henan University of Traditional Chinese Medicine
Collaborators
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Henan Provincial People's Hospital, Third Affiliated Hospital of Henan University of Traditional Chinese Medicine, Jiangsu province hospital of TCM, Qingdao Traditional Chinese Medicine Hospital(Qingdao Hiser Hospital), Xiangyang Traditional Chinese Medicine Hospital, Yanshi People's Hospital of Luoyang City, Shangcai County Traditional Chinese Medicine Hospital
Responsible party
Sponsor
First posted
Apr 9, 2025
Start date
Apr 1, 2025 (estimated)
Primary completion
Dec 31, 2028 (estimated)
Completion
Dec 31, 2028 (estimated)
Last update
Apr 11, 2025

Study contacts

Hailong H Zhang, doctor
Contact
zhanghailong6@126.com
+86-0371-66248624

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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