An interventional study of Mobilization with Movement and Joint Specific Manipulation in Tenosynovitis, sponsored by Riphah International University. Completed at 1 site in Pakistan. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-04-25.
Sponsored by Riphah International University · Not applicable, Interventional, and Health services research
A comparative study on the effectiveness of mobilization with movement (MWM) versus joint-specific manipulation (JSM) in patients with De Quervain's tenosynovitis typically aims to assess how each technique impacts pain relief and functional improvement. De Quervain's tenosynovitis is an inflammation of the tendons around the thumb and wrist, often causing pain, swelling, and difficulty in performing everyday tasks. The study would likely compare the two interventions by measuring pain levels, range of motion, and overall functional outcomes before and after treatment. MWM involves applying specific, controlled movements while the patient is actively engaging in their joint motion, targeting the tissue's mobility and reducing pain. JSM, on the other hand, focuses on manipulating the joint directly to restore normal function, specifically targeting the wrist and thumb regions affected by the condition.
A comparative study on the effectiveness of Mobilization with Movement (MWM) versus Joint-Specific Manipulation (JSM) in patients with De Quervain's Tenosynovitis would delve deeper into the physiological mechanisms and clinical outcomes associated with each technique, providing valuable evidence for therapeutic decision-making. De Quervain's Tenosynovitis is a condition characterized by the inflammation of the tendons at the base of the thumb, particularly affecting the abductor pollicis longus and extensor pollicis brevis tendons. This condition is commonly caused by repetitive strain, overuse, or trauma, leading to pain, swelling, and restricted movement, which significantly impacts the patient's daily activities.
Inclusion Criteria:o Patients clinically diagnosed with De Quervain's tenosynovitis
Exclusion Criteria:Participants fall in this category would be excluded of the study.
Group A
Other: Joint Specific Manipulation
Group B
Other: Mobilization with Movement
Mobilization with Movement * The proximal row of carpals glides passively radially. * Active thumb and wrist movements superimposed on the glide. Therapeutic excercises: * Ball Toss * Static web gripping * Gentle ROM activities to maintain mobility * Isometric exercises in all direction
Joint Specific Manipulation * High-velocity, low-amplitude thrust to the first carpometacarpal joint * Radiocarpal wrist mobilization .Grade III-IV applied at end range. 2. Therapeutic excercises: * Ball Toss * Static web gripping * Gentle ROM activities to maintain mobility * Isometric exercises in all direction Ergonomics modifications
Pain Reduction - Measured using the Numeric Pain Rating Scale (NPRS) (0-10 scale).
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), a validated tool where participants rate their pain on a scale from 0 no pain to 10 worst possible pain.
Time frame: 6 Months
Wrist Function - Assessed with the Patient-Rated Wrist Evaluation (PRWE) (0-100 scale).
Functional wrist use will be assessed using the Patient-Rated Wrist Evaluation (PRWE), which evaluates pain and disability on a 100-point scale, with higher scores indicating greater impairment. Clinical signs will be assessed using Finkelstein's Test, a standard diagnostic test for De Quervain's tenosynovitis, recorded as positive or negative. Data will be analyzed using pre- and post-intervention comparisons within and between groups to determine the effectiveness of each intervention.
Time frame: 6months
Clinical Signs - Evaluated using Finkelstein's Test (Positive/Negative).
Clinical Signs will be assessed using Finkelstein's Test, recorded as positive or negative based on the presence of pain during the maneuver.
Time frame: 6 months
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Riphah International University