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Active, not recruitingNCT06913478Updated Apr 6, 2025

Evaluation Of Effect of Axial Length on Cup-To-Disc Ratio Among Non- Glaucomatous Hypertensive Patients

An observational study in Hypertensive Complication, sponsored by Superior University. Active, not recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2025-04-06.

Sponsored by Superior University · Observational

From the registry’s dates

  • Primary completion was expected by Jun 2025, 1 year 3 months ago, but the record still lists the study as active, not recruiting.
Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
94
Ages
18 Years to 70 Years
Sex
All
01

Study summary

This observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital, with a sample size of 104 participants. A purposive sampling technique will be used.

Read the detailed description

Patients aged 18-70 years with systemic hypertension for at least one year and normal intraocular pressure will be included. Exclusion criteria include glaucoma, high myopia, hyperopia, ocular surgery, trauma, and optic nerve diseases. Axial length will be measured using optical biometry or A-scan ultrasonography, while the cup-to-disc ratio will be assessed through fundus examination using a slit lamp biomicroscope with a +90D lens or optical coherence tomography (OCT). Data will be meticulously documented, including patient demographics and medical history. The study will be completed within six months after approval, ensuring accurate and standardized measurements for reliable results.

02

Conditions studied

  • Hypertensive Complication
03

In context

Lead sponsor

Superior University is the lead sponsor of 242 studies on the registry; 24 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

his observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital

Inclusion criteria

  • Male and female patients diagnosed with systemic hypertension for at least 1 year.
  • Age between 18-70 years.
  • Normal intraocular pressure (IOP\<-21mmhg)
  • Axial length between 21mm and 26mm (to exclude extreme refractive errors)

Exclusion criteria

Exclusion Criteria:

  • History of glaucoma or ocular hypertension.
  • High myopia (\<-6.00 D) or hyperopia (>+6.00D).
  • History of ocular surgery, trauma, or retinal diseases.
  • Any optic nerve diseases.
05

Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
94 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Axial length measured by biometry and CD ratio by slitlamp

    The axial length, measured in millimeters, is defined as the distance from the anterior surface of the cornea to the retinal pigment epithelium. The axial length can be measured using either ultrasound biometry (accomplished via direct contact or immersion) or optical biometry

    Time frame: 12 Months

07

Study locations

1 site
  • Alshifa eye clinic Ali Pur chattha
    Gujrānwāla, Punjab, Pakistan
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 6, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06913478
Lead sponsor
Superior University
Responsible party
Muhammad Naveed Babur (Principal Investigator, Superior University) — Principal investigator
First posted
Apr 6, 2025
Start date
Mar 20, 2025
Primary completion
Jun 20, 2025 (estimated)
Completion
Feb 20, 2026 (estimated)
Last update
Apr 6, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

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