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CompletedNCT06891040Updated Apr 13, 2026

Phase II Clinical Study to Evaluate the Efficacy and Safety of VC005 in Adult Subjects With Mild to Moderate Atopic Dermatitis

A Phase 2 interventional study of VC005 Placebo group and VC005 groups in Atopic Dermatitis, sponsored by Jiangsu vcare pharmaceutical technology co., LTD. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-13.

Sponsored by Jiangsu vcare pharmaceutical technology co., LTD · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Enrollment
118
Allocation
Randomized
Ages
18 Years and older
Sex
All
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Study summary

A multicenter, randomized, double-blind, vehicle controlled phase II clinical study

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Conditions studied

  • Atopic Dermatitis

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03

In context

Dermatitis, Atopic

1,419 studies on the registry are indexed under Dermatitis, Atopic; 258 are open to participants now.

This study's enrollment of 118 is above the median of 83 across 1,125 interventional studies indexed under Dermatitis, Atopic.

Browse Dermatitis, Atopic studies →

Lead sponsor

Jiangsu vcare pharmaceutical technology co., LTD is the lead sponsor of 34 studies on the registry; 12 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Subjects fully understand this study, are able to follow the relevant procedures of the trial, voluntarily participate in the clinical trial, and sign the informed consent form (ICF);
  2. The age requirement for signing the ICF is 18 years old or above, with no gender restrictions;
  3. During screening, the diagnosis of atopic dermatitis should be met according to the Hanifin-Rajka criteria;

Exclusion criteria

Exclusion Criteria:

  1. Skin damage or abnormalities that may affect the evaluation of the administration site of the investigational drug;
  2. Skin diseases that are contraindicated in research or affect the evaluation of drug administration sites, including but not limited to psoriasis, acne, and skin cancer;
  3. Suffering from autoimmune diseases other than AD, such as inflammatory bowel disease and rheumatoid arthritis, and the researchers believe that this disease will be detrimental to the evaluation of this study;
  4. Current history of or presence of lymphoproliferative disorders, or signs or symptoms suggesting possible lymphoproliferative disorders, including lymphadenopathy or splenomegaly;
  5. Various malignant tumors, or any history of malignant tumors within the past 5 years prior to screening (excluding completely resected cervical carcinoma in situ, non metastatic squamous cell carcinoma, basal cell carcinoma, or papillary thyroid carcinoma);
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Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
118 participants (actual)

Study arms

  • Experimental
    VC005 Low Dose groups

    VC005 group with Local topical application

    Drug: VC005 groups

  • Experimental
    VC005 high Dose groups

    VC005 group with Local topical application

    Drug: VC005 groups

  • Placebo comparator
    VC005 Placebo groups

    VC005 Placebo group with Local topical application

    Drug: VC005 Placebo group

Interventions

  • DrugVC005 Placebo group

    VC005 Placebo group with Local topical application

  • DrugVC005 groups

    VC005 group with Local topical application

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What researchers measure

Primary outcomes

  1. Changes in EASI(Eczema area and severity index) from baseline

    Time frame: 8 week

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Study locations

1 site
  • Chinese Academy of Medical Sciences Hospital of Skin Disease
    Nanjing, Jiangsu, China
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 13, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06891040
Lead sponsor
Jiangsu vcare pharmaceutical technology co., LTD
Responsible party
Sponsor
First posted
Mar 24, 2025
Start date
Apr 28, 2025
Primary completion
Oct 31, 2025
Completion
Nov 4, 2025
Last update
Apr 13, 2026

Study contacts

Qian jin Lu
principal investigator · Chinese Academy of Medical Sciences Hospital of Skin Disease

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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