CClinicalTrials.gg
CompletedNCT06890936Updated Mar 24, 2025

Clinical Characteristics and Outcomes of Patients Requiring Mechanical Ventilation in an ICU- a Registry Based Study

An observational study in Mechanical Ventilation and Intensive Care Unit, sponsored by Tribhuvan University Teaching Hospital, Institute Of Medicine.. Completed at 1 site in Nepal. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-03-24.

Sponsored by Tribhuvan University Teaching Hospital, Institute Of Medicine. · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
1,800
Ages
18 Years and older
Sex
All
01

Study summary

Rationale: Patients admitted to the Intensive Care Unit (ICU) often require respiratory support in terms of mechanical ventilation (either non-invasive or invasive). Though these patients may be diverse in clinical characteristics, the need of respiratory support in itself is in many conditions a factor relating poorer outcomes. The exact association of the requirement of respiratory support in our patient population is missing in the current literature. This study will look at 5-year data of patients admitted to the ICUs of Tribhuvan University Teaching Hospital and try to characterize these patients according to their clinical profile. Further, this study will also help to generate data regarding the outcomes of such patients.

Study Objective: To characterize the patients requiring respiratory support in the ICUs of TUTH and find their outcomes in terms of ICU mortality.

Design: A registry based, retrospective, descriptive, cohort study. Sample size: Convenience sampling of all the patients who are admitted to the ICU.

Duration: Retrospective data from the 5-year period between November 1, 2019 to December 31, 2024.

Place: Intensive care units (ICUs), Tribhuvan University Teaching Hospital (TUTH).

Interventions: Not applicable Expected results: The study will help determine the clinical characteristics of patients admitted to the ICUs of TUTH requiring respiratory support and their associated outcomes.

02

Conditions studied

  • Mechanical Ventilation
  • Intensive Care Unit

Keywords

  • mechanical ventilation
  • intensive care unit
  • outcomes
03

In context

Lead sponsor

Tribhuvan University Teaching Hospital, Institute Of Medicine. is the lead sponsor of 40 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients admitted to the ICU

Inclusion criteria

  • Age>18 years
  • Admission to the ICU

Exclusion criteria

Exclusion Criteria:

None

05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
1,800 participants (actual)
Target follow-up
1 Day
Patient registry
Yes

Groups and cohorts

  • MV

    Patients requiring mechanical ventilation

06

What researchers measure

Primary outcomes

  1. ICU mortality

    Mortality during ICU stay

    Time frame: At the end of 5 years

07

Study locations

1 site
  • Tribhuvan University Teaching Hospital
    Maharajganj, Bagmati 44600, Nepal
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 24, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06890936
Lead sponsor
Tribhuvan University Teaching Hospital, Institute Of Medicine.
Responsible party
Bipin Karki (Dr., Tribhuvan University Teaching Hospital, Institute Of Medicine.) — Principal investigator
First posted
Mar 24, 2025
Start date
Nov 1, 2019
Primary completion
Dec 31, 2024
Completion
Dec 31, 2024
Last update
Mar 24, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion