An observational study in Cardiac Surgery Requiring Cardiopulmonary Bypass, sponsored by University Health Network, Toronto. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-03-19.
Sponsored by University Health Network, Toronto · Observational
The goal of this observational study is to determine the relationship of ROTEM point-of-care coagulation assay parameters with excessive bleeding and clinical outcomes in patients undergoing cardiac surgery at Toronto General Hospital. The main questions it aims to answer are: i) How well does viscoelastic testing (VET) predict the clinical outcome of excessive bleeding in cardiac surgery? ii) Which VET parameters have the greatest accuracy for identification of patients who will have excessive bleeding? iii) 3) What is the prognostic value of abnormal VET parameters with other clinical outcomes after cardiac surgery?
University Health Network, Toronto is the lead sponsor of 1,411 studies on the registry; 292 are open to participants now.
Of its 17 completed or terminated interventional studies of FDA-regulated products, 3 (18%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients undergoing cardiac surgery with cardiopulmonary bypass at Toronto General Hospital
Exclusion Criteria:
Adult patients undergoing cardiac surgery on cardiopulmonary bypass at Toronto General Hospital
Other: No intervention (observational study)
This is an observational study. No intervention.
Excessive bleeding
Measured by the universal definition of perioperative bleeding (UDPB) scale
Time frame: From the end of bypass to the end of postoperative day-1 (POD1)
Transfusion rate
Incidence and amount of transfusion of allogeneic blood products and factor concentrates
Time frame: 1) From time of entry to operating room (OR) to the end of post-operative day-1 (POD1) and post-operative day-7(POD7). 2) from end of cardiopulmonary bypass (CPB) to the end of post-operative day-1 (POD1) and post-operative day-7 (POD7)
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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University Health Network, Toronto