An interventional study of Optic nerve sheath diameter measurement 0 and optic nerve sheath diameter measurement 1 in Endotracheal Intubation During Surgery and Optic Nerve Sheath Diameter, sponsored by Ankara City Hospital Bilkent. Not yet recruiting at 1 site in Turkey. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-03-13.
Sponsored by Ankara City Hospital Bilkent · Not applicable, Interventional, and Diagnostic
This study aims to evaluate the effects of pre-intubation oropharyngeal topical lidocaine on optic nerve sheath diameter (ONSD) post-endotracheal intubation. The study will measure the ONSD using ultrasonography before intubation, and at 1, 5, and 10 minutes post-intubation. The results will be compared between patients receiving %10 lidocaine topically and %2 intravenous lidocaine.
Increased intracranial pressure (ICP) is a critical condition that requires early and accurate assessment. Traditional invasive ICP monitoring techniques, such as lumbar puncture and intracranial pressure monitoring devices, carry significant risks. Optic nerve sheath diameter (ONSD) measurement via ultrasonography is a non-invasive method that reflects increased ICP.
Patients will be divided into two groups: Group A will receive %10 topical oropharyngeal lidocaine, and Group B will receive %2 intravenous lidocaine. The primary aim of the study is to evaluate the impact of lidocaine on ONSD at 1, 5, and 10 minutes post-intubation and to compare the effects on the two groups.
Ankara City Hospital Bilkent is the lead sponsor of 424 studies on the registry; 105 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants will receive 10% lidocaine spray topically to the oropharynx before intubation.
Diagnostic Test: Optic nerve sheath diameter measurement 0 · Diagnostic Test: optic nerve sheath diameter measurement 1 · Diagnostic Test: optic nerve sheath diameter measurement 2 · Diagnostic Test: optic nerve sheath diameter measurement 3 · Procedure: Pre-intubation oropharyngeal topical %10 lidocaine
Participants will receive 2% lidocaine intravenously before intubation.
Diagnostic Test: Optic nerve sheath diameter measurement 0 · Diagnostic Test: optic nerve sheath diameter measurement 1 · Diagnostic Test: optic nerve sheath diameter measurement 2 · Diagnostic Test: optic nerve sheath diameter measurement 3 · Procedure: Pre-intubation intravenous %2 lidocaine
optic nerve sheath diameter (ONSD) measured via ultrasonography before intubation
optic nerve sheath diameter measurement 1 via ultrasonography after intubation 1st minute
optic nerve sheath diameter measurement via ultrasonography after intubation 5th minute
optic nerve sheath diameter measurement via ultrasonography after intubation 10th minute
Pre-intubation oropharyngeal topical %10 lidocaine
Pre-intubation intravenous %2 lidocaine
Optic nerve sheath diameter 0
optic nerve sheath diameter (ONSD) measured via ultrasonography before intubation
Time frame: Before intubation
Optic nerve sheath diameter 1
optic nerve sheath diameter (ONSD) measured via ultrasonography 1 minute after intubation
Time frame: 1 minute after intubation
Optic nerve sheath diameter 2
Optic nerve sheath diameter (ONSD) measured via ultrasonography 5 minutes after intubation
Time frame: 5 minutes after intubation
0ptic nerve sheath diameter 3
0ptic nerve sheath diameter (ONSD) measured via ultrasonography 10th minutes after intubation
Time frame: 10th minutes after intubation
Postoperative sore throat
Postoperative sore throat is evaluated with Visual Analog scale
Time frame: 1 hour after recovery room admission
Plan to share: Undecided — The individual participant data (IPD) will be made available upon request to scientific committees or researchers for further analysis, subject to ethical and privacy considerations.
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.
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Ankara City Hospital Bilkent