An observational study in Myasthenia Gravis and Dyspnea, sponsored by Institut de Myologie, France. Recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-08.
Sponsored by Institut de Myologie, France · Observational
Individuals with MG (IwMG) experience shortness of breath that may be activity-related, occur at rest and even happen during sleep. Dyspnea is a complex, multidimensional and multifactorial symptom involving sensory perception, cognition and emotion. Identifying the cause(s) of dyspnea in MG may assist in finding therapeutic strategies, reducing discomfort, improving QoL and potentially limiting respiratory deterioration and incidence of MG crisis.
MYaResp is a prospective observational, cross-sectional study to evaluate dyspnea in adults with autoimmune myasthenia gravis.
Study aims include to:
330 studies on the registry are indexed under Myasthenia Gravis; 144 are open to participants now.
This study's planned enrollment of 50 is below the median of 130 across 105 observational studies indexed under Myasthenia Gravis.
Browse Myasthenia Gravis studies →Institut de Myologie, France is the lead sponsor of 30 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Age ≥18 Confirmed diagnosis of autoimmune MG Shortness of breath in daily life: score 1 or 2 on the respiration item on the MG- activities of daily living score
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Autoimmune disease
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Dyspnea questionnaires
Dyspnea-12
Time frame: baseline
cardiopulmonary exercise test
cycle ergometer
Time frame: baseline
Polysomnography
evaluation of sleep disordered breathing
Time frame: baseline
Functional measures
6 minute walk test
Time frame: baseline
Quality of life questionnaires
Revised version of the myasthenia gravis quality of life questionnaire (Burns, French validation Birnbaum)
Time frame: baseline
Anxiety and depression
Hospital Anxiety and Depression Scale
Time frame: baseline
impact of myasthenia in daily living
impact of myasthenia in daily living score
Time frame: baseline
Respiratory pressures
inspiratory and expiratory pressures
Time frame: baseline
Plan to share: No
No publications or documents are linked to this record.
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No contact was published for this record. The registry link below has the sponsor’s details.
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Institut de Myologie, France